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Advanced filters: Author: James R. Troken Clear advanced filters

  • The mechanism of NLRP3 activation remains incompletely characterized. Here the authors show that it is dependent on vimentin, and that NLRP3-mediated lung injury and fibrosis induced by endotoxin, asbestos or bleomycin are reduced in vimentin-deficient mice.

    • Gimena dos Santos
    • Micah R. Rogel
    • Karen M. Ridge
    Research
    Nature Communications
    Volume: 6, P: 1-13