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Showing 1–4 of 4 results
Advanced filters: Author: Jan F. Jikeli Clear advanced filters
  • Sperm use external cues to find the egg using ill-defined principles. Here the authors use holographic microscopy and optochemical tools to study sperm swimming in light-sculpted chemical 3D landscapes; they show that sperm translate the temporal stimulation pattern into multiple swimming behaviours to orient deterministically in a gradient.

    • Jan F. Jikeli
    • Luis Alvarez
    • U. Benjamin Kaupp
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-10
  • Multifocal imaging suffers from a number of limitations. Here the authors report an open-source 3D reconstruction algorithm to enable label-free tracking of spherical and filamentous structures which they use to characterise fluid flow and flagellar beating of human and sea urchin sperm.

    • Jan N. Hansen
    • An Gong
    • Luis Alvarez
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15
  • The mechanism allowing sperm to steer is not fully understood. The authors find that superposition of two harmonic waves breaks the flagellar beat symmetry temporally rather than spatially, and that this mechanism is enhanced by the sexual hormone progesterone, which changes the motility pattern.

    • Guglielmo Saggiorato
    • Luis Alvarez
    • Jens Elgeti
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9