Nature Search

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Jose Florez, Claudia Langenberg, Erik Ingelsson, Inga Prokopenko, Inês Barroso and colleagues perform large-scale association analyses using the Metabochip to gain further insights into the genetic architecture of glucose regulation. They identify 38 new loci influencing 1 or more glycemic traits and show that many of these loci also modify risk of type 2 diabetes.

Robert A Scott
Vasiliki Lagou
Inês Barroso
Research12 Aug 2012
Nature Genetics

Volume: 44, P: 991-1005
Automated microinjection for zebrafish xenograft models

Yi Ding
Kees-Jan van der Kolk
Jan de Sonneville
ResearchOpen Access23 Apr 2025
npj Biomedical Innovations

Volume: 2, P: 1-11
Defining the role of common variation in the genomic and biological architecture of adult human height

Timothy Frayling, Joel Hirschhorn, Peter Visscher and colleagues report a meta-analysis of genome-wide association studies for adult height in 253,288 individuals. They identify 697 variants in 423 loci significantly associated with adult height and find that these variants cluster in pathways involved in growth and together explain one-fifth of the heritability for this trait.

Andrew R Wood
Tonu Esko
Timothy M Frayling
Research05 Oct 2014
Nature Genetics

Volume: 46, P: 1173-1186
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Erik Ingelsson and colleagues report a large-scale genome-wide meta-analysis for associations to the extremes of anthropometric traits, including body mass index, height, waist-to-hip ratio and clinical obesity. They identify four loci newly associated with height and seven loci newly associated with clinical obesity and find overlap in the genetic structure and distribution of variants identified for these extremes of the trait distributions and for the general population.

Sonja I Berndt
Stefan Gustafsson
Erik Ingelsson
Research07 Apr 2013
Nature Genetics

Volume: 45, P: 501-512
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Patricia Munroe, Christopher Newton-Cheh, Andrew Morris and colleagues perform association studies in over 340,000 individuals of European ancestry and identify 66 loci, of which 17 are novel, involved in blood pressure regulation. The risk SNPs are enriched for cis-regulatory elements, particularly in vascular endothelial cells.

Georg B Ehret
Teresa Ferreira
Patricia B Munroe
Research12 Sept 2016
Nature Genetics

Volume: 48, P: 1171-1184
A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out

Jelmer Hoeksma
Tim Misset
Jeroen den Hertog
ResearchOpen Access26 Nov 2019
Scientific Reports

Volume: 9, P: 1-16
Author Correction: Priority list of biodiversity metrics to observe from space

Andrew K. Skidmore
Nicholas C. Coops
Vladimir Wingate
Amendments and Corrections25 Oct 2021
Nature Ecology & Evolution

Volume: 5, P: 1639
Author Correction: Priority list of biodiversity metrics to observe from space

Andrew K. Skidmore
Nicholas C. Coops
Vladimir Wingate
Amendments and Corrections19 Jul 2021
Nature Ecology & Evolution

Volume: 5, P: 1318
Author Correction: Priority list of biodiversity metrics to observe from space

Andrew K. Skidmore
Nicholas C. Coops
Vladimir Wingate
Amendments and Corrections24 May 2021
Nature Ecology & Evolution

Volume: 5, P: 1046
Greenhouse gas emissions and mitigation in rice agriculture

Rice paddies account for a large proportion of total agricultural methane and nitrous oxide emissions. This Review outlines the characteristics, changes and mitigation options for these emissions, highlighting the benefits of water and organic matter management.

Haoyu Qian
Xiangchen Zhu
Yu Jiang
Reviews26 Sept 2023
Nature Reviews Earth & Environment

Volume: 4, P: 716-732
Priority list of biodiversity metrics to observe from space

Remote sensing of geospatial biodiversity patterns is an important complement to field observations. This priority list suggests how remote sensing observations can be better integrated into the essential biodiversity variables.

Andrew K. Skidmore
Nicholas C. Coops
Vladimir Wingate
Reviews13 May 2021
Nature Ecology & Evolution

Volume: 5, P: 896-906

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