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Advanced filters: Author: Jan Philipp Dobert Clear advanced filters

  • The lysosomal enzyme beta-glucocerebrosidase is a key player and promising therapeutic target in Parkinson’s disease. Here, Dobert et al. leveraged cryo-EM to solve the protein structure of the enzyme in complex with its lysosomal transporter LIMP-2.

    • Jan Philipp Dobert
    • Jan-Hannes Schäfer
    • Philipp Arnold
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14