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Showing 1–4 of 4 results
Advanced filters: Author: Janice L Brissette Clear advanced filters

  • A new study identifies mutations in the HR gene as the cause of Marie Unna hereditary hypotrichosis (MUHH). The mutations seem to disrupt an unusual leader sequence–based mechanism of translational repression, making MUHH the first example of a disease linked to this form of repression.

    • Lorin Weiner
    • Janice L Brissette
    News & Views
    Nature Genetics
    Volume: 41, P: 141-142

  • Skin is constantly exposed to environmental stressors. Georgopoulos and colleagues show that regulatory T cells respond to the cytokine TSLP produced by stressed keratinocytes and that a loss of skin Treg cell expression of TSLPR leads to lethal inflammation.

    • Mariko Kashiwagi
    • Junichi Hosoi
    • Katia Georgopoulos
    Research
    Nature Immunology
    Volume: 18, P: 334-343