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Showing 1–2 of 2 results
Advanced filters: Author: Janine Baaten Clear advanced filters

  • An organoid-based screening platform maps the genetic interactions underlying intestinal development and regeneration, showing that retinoic acid metabolism maintains the balance between regeneration and homeostasis, and that an antagonist of the retinoid X receptor promotes regeneration in vivo.

    • Ilya Lukonin
    • Denise Serra
    • Prisca Liberali
    Research
    Nature
    Volume: 586, P: 275-280

  • High-throughput chemical screening identified several groups of compounds that selectively block superoxide production from the outer Q-binding site of mitochondrial complex III and protect against ROS-induced oxidative stress in pancreatic β cells.

    • Adam L Orr
    • Leonardo Vargas
    • Martin D Brand
    Research
    Nature Chemical Biology
    Volume: 11, P: 834-836