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Showing 1–2 of 2 results
Advanced filters: Author: Janyerkye Tulyeu Clear advanced filters

  • Traditional regulatory T cell (Tregs) assays utilize mixture of purified cell population. Here the authors develop a ‘single cell suppression profiling of human Tregs’ (scSPOT) with 52-marker CyTOF panel, a cell division detection algorithm, and a whole PBMC system to assess Treg suppressive function on all cell types simultaneously.

    • Jonas Nørskov Søndergaard
    • Janyerkye Tulyeu
    • James B. Wing
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Activated memory B cells express a variety of markers. Here, by mass cytometry and CITE-seq, the authors identify differential expression of CD45RB as a marker distinguishing classical and atypical/non-classical memory B cells, with the former being more prominent during sepsis, while the latter being more abundant in COVID-19 infection or vaccination.

    • David G. Priest
    • Takeshi Ebihara
    • James B. Wing
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21