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Showing 1–2 of 2 results
Advanced filters: Author: Jasmin Mangei Clear advanced filters

  • Glioblastoma is divided into four subtypes based on molecular profiling at the methylome and transcriptome level. Here the authors perform an integrative analysis of these subtypes resulting in the identification of SOX10 whose loss induces a mesenchymal phenotype and promotes tumour progression.

    • Yonghe Wu
    • Michael Fletcher
    • Bernhard Radlwimmer
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-19

  • Long noncoding RNAs (lncRNAs) regulate key steps of cell division. Here, the authors perform a comprehensive RNAi imaging screen targeting more than 2,000 human lncRNAs, and suggest a role of chromatin-associated linc00899 in regulation of cell division by suppressing the transcription of microtubule-binding protein TPPP/p25.

    • Lovorka Stojic
    • Aaron T. L. Lun
    • Fanni Gergely
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-21