Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Jason Bugno Clear advanced filters

  • Radiotherapy induces expression of the EGFR ligand amphiregulin, which promotes metastasis growth at remote sites in mouse models and human patients by shifting myeloid cells towards an immunosuppressive state.

    • András Piffkó
    • Kaiting Yang
    • Ralph R. Weichselbaum
    Research
    Nature
    Volume: 643, P: 810-819

  • Activation of the stimulator of interferon genes (STING) can induce immunity in various cancer therapies, but delivery of STING agonists to tumours is challenging. Now a metal-based polymeric nanoparticle delivers STING agonists to tumours upon disruption of endothelial cells in tumour vasculature and targets tumour-associated macrophages, eliciting anti-tumour immune response in hard-to-treat cancer models.

    • Kaiting Yang
    • Wenbo Han
    • Ralph R. Weichselbaum
    Research
    Nature Nanotechnology
    Volume: 17, P: 1322-1331

  • Mir-22 has been shown to be an oncogenic microRNA in breast cancer and myelodysplastic syndrome. Here, the authors show that mir-22 functions as a tumour suppressor in de novoacute myeloid leukaemia by inhibiting the expression of several oncogenes and that restoring mir-22 expression suppresses AML progression.

    • Xi Jiang
    • Chao Hu
    • Jianjun Chen
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-15