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Showing 1–3 of 3 results

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Genes driving three-dimensional growth of immortalized cells and cancer

Mukta Basu
Jin-Fen Xiao
Dan Theodorescu
ResearchOpen Access10 Jun 2025
Cell Death & Disease

Volume: 16, P: 1-11
Advances in bladder cancer biology and therapy

This Review examines recent developments in the molecular and translational aspects of bladder cancer biology and discusses their current or potential future clinical applications in the management of bladder cancer.

Linda Tran
Jin-Fen Xiao
Dan Theodorescu
Reviews02 Dec 2020
Nature Reviews Cancer

Volume: 21, P: 104-121
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy

Investigating signalling induced by the cytokine CCL2 as a therapeutic target, Tu et al demonstrate that blockade of the CCL2 receptor, CCR2 enhances CD8+ T cell recruitment and activation and the therapeutic efficacy of PD-1 inhibition in tumours.

Megan M. Tu
Hany A. Abdel-Hafiz
Dan Theodorescu
ResearchOpen Access27 Nov 2020
Communications Biology

Volume: 3, P: 1-12