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Showing 1–10 of 10 results
Advanced filters: Author: Jason Lloyd-Price Clear advanced filters

  • Inflammatory bowel diseases (IBD) are associated with increased faecal N-acylethanolamines (NAEs), which are primarily host-produced signalling lipids, in patients and a mouse model of colitis. These metabolites can enhance the growth of bacterial species enriched in IBD faecal samples and are associated with the expression of respiratory chain genes necessary for microbial metabolism of NAEs.

    • Nadine Fornelos
    • Eric A. Franzosa
    • Ramnik J. Xavier
    Research
    Nature Microbiology
    Volume: 5, P: 486-497

  • Metabolomics data from germ-free and specific-pathogen-free mice reveal effects of the microbiome on host chemistry, identifying conjugations of bile acids that are also enriched in patients with inflammatory bowel disease or cystic fibrosis.

    • Robert A. Quinn
    • Alexey V. Melnik
    • Pieter C. Dorrestein
    Research
    Nature
    Volume: 579, P: 123-129

  • The Inflammatory Bowel Disease Multi’omics Database includes longitudinal data encompassing a multitude of analyses of stool, blood and biopsies of more than 100 individuals, and provides a comprehensive description of host and microbial activities in inflammatory bowel diseases.

    • Jason Lloyd-Price
    • Cesar Arze
    • Curtis Huttenhower
    ResearchOpen Access
    Nature
    Volume: 569, P: 655-662

  • Metagenomic and metatranscriptomic analyses of stool samples from 308 individuals over time indicate that longitudinal sampling is important for detecting dynamic functional features of the gut microbiome.

    • Raaj S. Mehta
    • Galeb S. Abu-Ali
    • Andrew T. Chan
    Research
    Nature Microbiology
    Volume: 3, P: 347-355

  • Analysis of human faecal metatranscriptomes and metagenomes reveals core and variable metatranscriptomes across time and individuals, and similar strain-level variation within and between subjects, providing further insights into human microbial ecology.

    • Galeb S. Abu-Ali
    • Raaj S. Mehta
    • Curtis Huttenhower
    Research
    Nature Microbiology
    Volume: 3, P: 356-366

  • Analysis of paired metagenomes and metatranscriptomes associated with patients with inflammatory bowel disease (IBD) and non-IBD controls over time provides some insights into microbial community variation and potential pathways influencing IBD symptoms.

    • Melanie Schirmer
    • Eric A. Franzosa
    • Curtis Huttenhower
    Research
    Nature Microbiology
    Volume: 3, P: 337-346

  • Over ten years, the Human Microbiome Project has provided resources for studying the microbiome and its relationship to disease; this Perspective summarizes the key achievements and findings of the project and its relationship to the broader field.

    • Lita M. Proctor
    • Heather H. Creasy
    • Curtis Huttenhower
    ReviewsOpen Access
    Nature
    Volume: 569, P: 641-648