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Showing 1–3 of 3 results
Advanced filters: Author: Jason M. Lynam Clear advanced filters
  • Although mechanistic understanding can drive new reactivity development, the key bond-forming and -breaking steps in catalytic cycles are often sufficiently fast to elude observation. Here, the authors photochemically produce a key intermediate in Mn-catalysed C–H functionalization, and follow the subsequent steps—spanning processes occurring over seven orders of magnitude in time—using time-resolved infrared spectroscopy.

    • L. Anders Hammarback
    • Ian P. Clark
    • Jason M. Lynam
    Research
    Nature Catalysis
    Volume: 1, P: 830-840
  • Knowledge about the full reaction signature, such as the complete profile of products and side-products is important in accelerating discovery chemistry. Here, the authors report a methodology using high-throughput experimentation and multivariate data analysis to examine Palladium- catalyzed cross-coulpling reactions.

    • George E. Clarke
    • James D. Firth
    • Ian J. S. Fairlamb
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15