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Showing 1–2 of 2 results
Advanced filters: Author: Jasper Akerboom Clear advanced filters

  • An improved version of the GCaMP genetically encoded calcium indicator, called GCaMP3, has higher calcium affinity and increased baseline fluorescence, dynamic range and stability. GCaMP3 performs better than existing genetically encoded calcium indicators in several assays and organisms, including in vivo imaging of neuronal signaling in worms, flies and mice.

    • Lin Tian
    • S Andrew Hires
    • Loren L Looger
    Research
    Nature Methods
    Volume: 6, P: 875-881

  • A single-wavelength genetically encoded sensor of extracellular glutamate is reported. The sensor—iGluSnFR—is bright and photostable under both one- and two-photon illumination and is shown to work for in vivo imaging in worms, zebrafish and mice.

    • Jonathan S Marvin
    • Bart G Borghuis
    • Loren L Looger
    Research
    Nature Methods
    Volume: 10, P: 162-170