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Showing 1–5 of 5 results
Advanced filters: Author: Jatin M. Vyas Clear advanced filters

  • The pathways of antigen processing and presentation are well known, but how do antigens gain access to MHC molecules in dendritic cells and what is the role of autophagy, endoplasmic reticulum dislocation and Toll-like receptors in these pathways?

    • Jatin M. Vyas
    • Annemarthe G. Van der Veen
    • Hidde L. Ploegh
    Reviews
    Nature Reviews Immunology
    Volume: 8, P: 607-618

  • Natural killer (NK) cells has been show to mediate fungi killing via the activating receptor NKp30, but the fungal target for NKp30 is still unclear. Here the authors show, using atomic force microscopy and live cell imaging, that β-1,3-glucan is expressed by Cryptococcus neoformans and Candida albicans and responsible for NKp30-mediated NK killing.

    • Shu Shun Li
    • Henry Ogbomo
    • Christopher H. Mody
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • Integrins can regulate antigen-specific and innate immune receptor signalling, thereby affecting immune cell function. Here the authors show that avß3 integrin controls Toll-like receptor (TLR) signalling by regulating its trafficking to limit TLR-mediated B-cell proliferation and antibody production.

    • Mridu Acharya
    • Anna Sokolovska
    • Adam Lacy-Hulbert
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-15