Information-bearing templates that catalyse the assembly of complex macromolecules are a central motif of natural biochemistry, but their power remains largely unexplored in synthetic contexts. Enzyme-free templating of DNA dimerization has now been demonstrated, using DNA nanotechnology to ensure that the templates are effective information-propagating catalysts.
- Javier Cabello-Garcia
- Rakesh Mukherjee
- Thomas E. Ouldridge
