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Advanced filters: Author: Javier Lizarrondo Clear advanced filters

  • During clathrin-mediated endocytosis in yeast, endocytic coat adaptors, Sla2 and Ent1, must remain attached to the plasma membrane to transmit force from the actin cytoskeleton required for membrane invagination. Here authors present a cryo-EM structure of a 16-mer complex of the ANTH and ENTH membrane-binding domains from Sla2 and Ent1 bound to PIP2 that constitutes the anchor to the plasma membrane.

    • Javier Lizarrondo
    • David P. Klebl
    • Maria M. Garcia-Alai
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15