The encapsulation of a drug into nanoparticles can be a useful way control and improve its efficacy. Here, the authors conjugate paclitaxel to recombinant chimeric polypeptides that self-assemble into therapeutic nanoparticles that outperform Abraxane in murine tumour models.
- Jayanta Bhattacharyya
- Joseph J. Bellucci
- Ashutosh Chilkoti
