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Advanced filters: Author: Jayati Chakrabarti Clear advanced filters

VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1

VacA promotes Helicobacter pylori intracellular localization and persistence in the face of antibiotics. Activation of the lysosomal TRPML1 calcium channel reverses VacA toxicity and promotes bacterial clearance during drug treatment.

Mariana I. Capurro
Laura K. Greenfield
Nicola L. Jones
Research20 May 2019
Nature Microbiology

Volume: 4, P: 1411-1423
Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium

Jayati Chakrabarti
Martha Dua-Awereh
Yana Zavros
ResearchOpen Access12 Jan 2022
npj Regenerative Medicine

Volume: 7, P: 1-16
H. pylori infection confers resistance to apoptosis via Brd4-dependent BIRC3 eRNA synthesis

Yanheng Chen
Donald Sheppard
Lin-Feng Chen
ResearchOpen Access21 Aug 2020
Cell Death & Disease

Volume: 11, P: 1-14

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