Mice lacking 4E-BP2, an eIF4E repressor, display increased translation of neuroligins; the mice also show autism-related behaviours and alterations in hippocampal synaptic activity, and these are reversed by normalization of eIF4E activity or neuroligin 1 levels.
- Christos G. Gkogkas
- Arkady Khoutorsky
- Nahum Sonenberg