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Advanced filters: Author: Jean-Christophe M. Monbaliu Clear advanced filters

  • Flow-based peptide synthesis is a well-established method, yet difficult to combine with native chemical ligation (NCL), the go-to method for peptide cyclization. Here, the authors developed a microfluidic procedure for peptide cyclization within minutes, using NCL and an SEA alkylthioester peptide.

    • Nathalie Ollivier
    • Thomas Toupy
    • Oleg Melnyk
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12