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Showing 1–4 of 4 results
Advanced filters: Author: Jean-Francois Dubremetz Clear advanced filters

  • John C. Boothroyd and Jean-Francois Dubremetz review the roles of the apical rhoptry organelles in cell invasion by Apicomplexan parasites such asToxoplasma gondii and Plasmodiumspp. They propose a model in which an expansion of host range might have been the selective pressure for rhoptry-protein evolution.

    • John C. Boothroyd
    • Jean-Francois Dubremetz
    Reviews
    Nature Reviews Microbiology
    Volume: 6, P: 79-88

  • Apicomplexa include important human pathogens and possess a unique cellular machinery that promotes gliding motility and is called the glideosome. In this Review, Soldati-Favre and colleagues discuss the principles that govern gliding motility, the characterization of the molecular machinery that comprises the glideosome, and its impact on parasite invasion and egress from infected cells.

    • Karine Frénal
    • Jean-François Dubremetz
    • Dominique Soldati-Favre
    Reviews
    Nature Reviews Microbiology
    Volume: 15, P: 645-660

  • Mice engrafted with human cells are useful models for research on human malaria parasites. Here the authors show that the complete life cycle of Plasmodium falciparum and the liver stages of Plasmodium ovalecan be studied in mice doubly engrafted with human primary hepatocytes and red blood cells.

    • Valérie Soulard
    • Henriette Bosson-Vanga
    • Dominique Mazier
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-9