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Advanced filters: Author: Jeffery Dickhout Clear advanced filters

  • PTEN is a phosphatase that regulates the phosphatidylinositol-3 kinase signalling pathway and is inactivated in many tumour types. Heet al.show that a mannosidase, α-mannosidase 2C1, can inactivate PTEN in prostate cancer cells, and that PTEN-positive human prostate tumours overexpress α-mannosidase 2C1.

    • Lizhi He
    • Catherine Fan
    • Damu Tang
    Research
    Nature Communications
    Volume: 2, P: 1-11