Nature Search

The Knowledge Connector decision support system for multiomics-based precision oncology

Integrating complex multi-omics data for individual patient decision making can be challenging. Here, the authors develop Knowledge Connector as a decision support system to generate and document Molecular Tumor Board recommendations and support medical decision-making.

Daniel Hübschmann
Simon Kreutzfeldt
Peter Horak
ResearchOpen Access19 Jan 2026
Nature Communications

Volume: 17, P: 1-12
Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study

Estimates from the Global Burden of Disease study reveal declines in chronic respiratory disease mortality between 1990 and 2023—especially during the COVID-19 pandemic—but the burdens on people affected remain substantial.

Jiyeon Oh
Soeun Kim
Dong Keon Yon
Research06 Jan 2026
Nature Medicine

Volume: 32, P: 197-223
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Genomic reconstruction of the SARS-CoV-2 epidemic in England

A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
ResearchOpen Access14 Oct 2021
Nature

Volume: 600, P: 506-511
Ocean acidification can mediate biodiversity shifts by changing biogenic habitat

How ocean acidification will impact coastal biogenic habitats is unclear. This study predicts that indirect effects on habitat-forming organisms, combined with direct effects on biodiversity, will cause changes in structural complexity and extent of these habitats.

Jennifer M. Sunday
Katharina E. Fabricius
Christopher D. G. Harley
Research21 Nov 2016
Nature Climate Change

Volume: 7, P: 81-85
Global music streaming data reveal diurnal and seasonal patterns of affective preference

Using data from 765 million online music plays chosen by 1 million individuals in 51 countries, Park et al. reveal diurnal and seasonal affective rhythms in musical intensity that are consistent across diverse cultures and demographic groups. They also report differences in baseline preferences for musical intensity across cultures and ages.

Minsu Park
Jennifer Thom
Michael Macy
Research21 Jan 2019
Nature Human Behaviour

Volume: 3, P: 230-236
Behaviourally modulated hippocampal theta oscillations in the ferret persist during both locomotion and immobility

Cross-species research is key to fully understanding brain function. Here, the authors present the ferret as a species for hippocampal research and show that, in stark contrast to rats, ferrets have robust theta oscillations during immobility.

Soraya L. S. Dunn
Stephen M. Town
Daniel Bendor
ResearchOpen Access07 Oct 2022
Nature Communications

Volume: 13, P: 1-20
Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.

Sooji Lee
Yejun Son
Nicholas. J. Kassebaum
Research22 Apr 2025
Nature Medicine

Volume: 31, P: 1809-1829
Climate drives global functional trait variation in lizards

The authors incorporate mechanistic information about lizard physiological responses to heat into predictions of trait variation across time and space, finding that the range of functional traits is more constrained in locations where the local climate strongly selects for thermal performance.

Juan G. Rubalcaba
Sidney F. Gouveia
Jennifer Sunday
Research06 Mar 2023
Nature Ecology & Evolution

Volume: 7, P: 524-534
The pace of biodiversity change in a warming climate

The timing of disruptions to biodiversity associated with global warming is a key, but little-explored, dimension of change. Will losses in biodiversity occur all at once, or be spread out over time?

Jennifer M. Sunday
News & Views08 Apr 2020
Nature

Volume: 580, P: 460-461
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

An integrated analysis of de novo and inherited coding variants in 42,607 individuals with autism spectrum disorder identifies 60 risk genes of which five have not previously been associated with neurodevelopmental disorders.

Xueya Zhou
Pamela Feliciano
Wendy K. Chung
ResearchOpen Access18 Aug 2022
Nature Genetics

Volume: 54, P: 1305-1319
Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

For many neurodevelopmental disorder (NDD) risk genes, the significance for mutational burden is unestablished. Here, the authors sequence 125 candidate NDD genes in over 16,000 NDD cases; case-control mutational burden analysis identifies 48 genes with a significant burden of severe ultra-rare mutations.

Tianyun Wang
Kendra Hoekzema
Evan E. Eichler
ResearchOpen Access01 Oct 2020
Nature Communications

Volume: 11, P: 1-13
Temperate species underfill their tropical thermal potentials on land

The authors test whether a wide array of marine and terrestrial animal species occupy the full extent of their potential geographic range based on thermal tolerances. They find that many species are underfilling the warm part of their potential range, suggesting that biotic interactions can limit occupancy in climatically suitable areas adjacent to their ranges.

Nikki A. Moore
Ignacio Morales-Castilla
Jennifer M. Sunday
ResearchOpen Access06 Nov 2023
Nature Ecology & Evolution

Volume: 7, P: 1993-2003
The evolution of critical thermal limits of life on Earth

Historical climate adaptation can give insight into the potential for adaptation to contemporary changing climates. Here Bennett et al. investigate thermal tolerance evolution across much of the tree of life and find different effects of ancestral climate on the subsequent evolution of ectotherms vs. endotherms.

Joanne M. Bennett
Jennifer Sunday
Miguel Ángel Olalla-Tárraga
ResearchOpen Access19 Feb 2021
Nature Communications

Volume: 12, P: 1-9
Measuring dynamic social contacts in a rehabilitation hospital: effect of wards, patient and staff characteristics

Audrey Duval
Thomas Obadia
Isabelle Villain
ResearchOpen Access26 Jan 2018
Scientific Reports

Volume: 8, P: 1-11
Data-driven testing program improves detection of COVID-19 cases and reduces community transmission

Steven J. Krieg
Carolina Avendano
Nitesh V. Chawla
ResearchOpen Access11 Feb 2022
npj Digital Medicine

Volume: 5, P: 1-5
Uteroplacental Insufficiency Lowers the Cerebral Threshold towards Hypoxia Induced Apoptosis in Fetal Rats

Robert H Lane
Rolondo J Ramierez
Elisa M Gruetzmacher
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 55
Autoantigen Specific CD4+ T Cell Responses in Children with Type 1 Diabetes Mellitus and Healthy Controls

Jennifer A Olson
Sarah L Parry
Grete Sonderstrup
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 95
Thermal tolerance and the global redistribution of animals

Using a comprehensive data set of thermal tolerance limits, latitudinal range boundaries and latitudinal range shifts of cold-blooded animals, this study explores the likely consequences of climate change for the geographical redistribution of terrestrial and marine species at a global scale.

Jennifer M. Sunday
Amanda E. Bates
Nicholas K. Dulvy
Research27 May 2012
Nature Climate Change

Volume: 2, P: 686-690
Social distancing and extremely preterm births in the initial COVID-19 pandemic period

Vivek V. Shukla
Benjamin A. Carper
Kathryn D. Woodbury
ResearchOpen Access22 Feb 2024
Journal of Perinatology

Volume: 44, P: 1050-1057
Understanding activity and physiology at scale: The Apple Heart & Movement Study

James Truslow
Angela Spillane
Calum A. MacRae
ResearchOpen Access10 Sept 2024
npj Digital Medicine

Volume: 7, P: 1-11
Author Correction: Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

Tianyun Wang
Kendra Hoekzema
Evan E. Eichler
Amendments and CorrectionsOpen Access21 Oct 2020
Nature Communications

Volume: 11, P: 1
Greater vulnerability to warming of marine versus terrestrial ectotherms

Comparisons across terrestrial and marine ectotherms reveal that marine species experience temperatures closer to their upper thermal limits, and that local extirpations related to warming are more common in the ocean.

Malin L. Pinsky
Anne Maria Eikeset
Jennifer M. Sunday
Research24 Apr 2019
Nature

Volume: 569, P: 108-111
Autonomous artificial intelligence increases real-world specialist clinic productivity in a cluster-randomized trial

Michael D. Abramoff
Noelle Whitestone
Khairul Islam
ResearchOpen Access04 Oct 2023
npj Digital Medicine

Volume: 6, P: 1-8
Passive acoustic monitoring of beaked whale densities in the Gulf of Mexico

John A. Hildebrand
Simone Baumann-Pickering
Len Thomas
ResearchOpen Access12 Nov 2015
Scientific Reports

Volume: 5, P: 1-15
Mechanisms, detection and impacts of species redistributions under climate change

Warming temperatures driven by climate change are causing species geographic ranges to shift, but factors such as habitat characteristics and species interactions impact these changes. This Review examines range shift documentation, how shifts differ from temperature-based expectations, and the effects of range shifts on natural and human systems.

Jake A. Lawlor
Lise Comte
Jennifer Sunday
Reviews18 Apr 2024
Nature Reviews Earth & Environment

Volume: 5, P: 351-368
Household illness and associated water and sanitation factors in peri-urban Lusaka, Zambia, 2016–2017

Sydney C. Hubbard
Martin I. Meltzer
Joan M. Brunkard
ResearchOpen Access04 Jun 2020
npj Clean Water

Volume: 3, P: 1-7
Enhanced physical and cognitive performance in active duty Airmen: evidence from a randomized multimodal physical fitness and nutritional intervention

Christopher E. Zwilling
Adam Strang
Aron K. Barbey
ResearchOpen Access19 Oct 2020
Scientific Reports

Volume: 10, P: 1-13
Genome sequencing identifies multiple deleterious variants in autism patients with more severe phenotypes

Hui Guo
Michael H. Duyzend
Evan E. Eichler
Research03 Dec 2018
Genetics in Medicine

Volume: 21, P: 1611-1620
Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes

Pamela Feliciano
Xueya Zhou
Wendy K. Chung
ResearchOpen Access23 Aug 2019
npj Genomic Medicine

Volume: 4, P: 1-14
#InSituPathologists: how the #USCAP2015 meeting went viral on Twitter and founded the social media movement for the United States and Canadian Academy of Pathology

David Cohen
Timothy Craig Allen
Jerad M Gardner
Editorial13 Jan 2017
Modern Pathology

Volume: 30, P: 160-168
GlobTherm, a global database on thermal tolerances for aquatic and terrestrial organisms

Joanne M. Bennett
Piero Calosi
Ignacio Morales-Castilla
ResearchOpen Access13 Mar 2018
Scientific Data

Volume: 5, P: 1-7

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