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Advanced filters: Author: Jeremi Kuklewicz Clear advanced filters

  • A cryo-electron microscopy analysis reveals how HAS selects its substrates, hydrolyses the first substrate to prime the synthesis reaction, opens a hyaluronan-conducting transmembrane channel, ensures alternating substrate polymerization and coordinates hyaluronan inside its transmembrane pore.

    • Finn P. Maloney
    • Jeremi Kuklewicz
    • Jochen Zimmer
    Research
    Nature
    Volume: 604, P: 195-201

  • An ensemble of cryo-electron microscopy structures of the KpsMT ABC transporter in complex with the KpsE co-polymerase and a glycolipid substrate reveal how capsular polysaccharides are recognized and translocated across bacterial cell membranes.

    • Jeremi Kuklewicz
    • Jochen Zimmer
    ResearchOpen Access
    Nature
    Volume: 628, P: 901-909