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Showing 1–2 of 2 results
Advanced filters: Author: Jeremy H. Lakey Clear advanced filters

  • The O-antigen of LPS is known to limit the binding of antibody to bacterial surface antigens. Here the AUs show that the chemical and physical structure of the O-antigen are central factors in limiting the exposure of surface antigens to antibodies during Salmonella infection, thus defining their protective qualities.

    • C. Coral Domínguez-Medina
    • Marisol Pérez-Toledo
    • Adam F. Cunningham
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Chloride regulation is important for setting GABAergic reversal potential, though tools to manipulate chloride levels are limited. Here, the authors combine Archaerhodopsin with a chloride channel opsin to generate an optogenetic chloride extrusion strategy, ‘Cl-out’, which they demonstrate in hippocampal slices.

    • Hannah Alfonsa
    • Jeremy H. Lakey
    • Andrew J. Trevelyan
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-9