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Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound

Andrew H. J. Wang
Jeremy Nathans
Alexander Rich
Research30 Nov 1978
Nature

Volume: 276, P: 471-474
Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9

Amphihelical antimicrobial peptides (AMPs) are bactericidal host defense factors, but their function as immunomodulators is emerging. Here the authors show that several AMPs organize DNA into periodic nanocrystals by self-assembling into superhelical protofibril scaffolds, which potentiates DNA sensing by TLR9.

Ernest Y. Lee
Changsheng Zhang
Gerard C. L. Wong
ResearchOpen Access04 Mar 2019
Nature Communications

Volume: 10, P: 1-10
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Most studies of the genetics of the metabolome have been done in individuals of European descent. Here, the authors integrate genomics and metabolomics in Black individuals, highlighting the value of whole genome sequencing in diverse populations and linking circulating metabolites to human disease.

Usman A. Tahir
Daniel H. Katz
Robert E. Gerszten
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Dynamical dark energy in light of the latest observations

Recent observations reveal tension between various cosmological probes. Assuming dark energy to be non-constant, depending on redshift, may relieve this tension. The Dark Energy Spectroscopic Instrument survey will be able to confirm this result.

Gong-Bo Zhao
Marco Raveri
Hanyu Zhang
Research28 Aug 2017
Nature Astronomy

Volume: 1, P: 627-632
Exceptional atmospheric conditions in June 2023 generated a northwest European marine heatwave which contributed to breaking land temperature records

The June 2023 marine heatwave over the northwest shelf of Europe developed rapidly with weak winds, strong insolation and low wave activity, and led to temperature records in northern Europe, according to an analysis of in situ measurements, satellite data and model simulations.

Ségolène Berthou
Richard Renshaw
Mark Worsfold
ResearchOpen Access30 May 2024
Communications Earth & Environment

Volume: 5, P: 1-11

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Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound

Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9

Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Dynamical dark energy in light of the latest observations

Exceptional atmospheric conditions in June 2023 generated a northwest European marine heatwave which contributed to breaking land temperature records

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