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Showing 1–13 of 13 results
Advanced filters: Author: Jerome Cantor Clear advanced filters

  • Researchers have constructed a terahertz quantum cascade laser using quasi-periodic distributed feedback gratings based on the Fibonacci sequence. Features that go beyond traditional distributed feedback lasers are demonstrated, such as directional output independent of the emission frequency and multicolour operation.

    • Lukas Mahler
    • Alessandro Tredicucci
    • Diederik S. Wiersma
    Research
    Nature Photonics
    Volume: 4, P: 165-169

  • Etienne Bucher and colleagues use a combination of short- and long-read sequencing, along with optical mapping technologies, to produce the high-quality de novo assembly of the apple genome. They identify a new repetitive retrotransposon sequence and analyze DNA methylation data in relation to important agronomic traits.

    • Nicolas Daccord
    • Jean-Marc Celton
    • Etienne Bucher
    ResearchOpen Access
    Nature Genetics
    Volume: 49, P: 1099-1106

  • Stewart Cole and colleagues report the genome sequence and comparative analyses of Brazilian, Indian, North American and Thai strains of Mycobacterium leprae, the etiologial agent of leprosy. They define 16 sub-types of M. leprae and examine their geographical distribution.

    • Marc Monot
    • Nadine HonorĂ©
    • Stewart T Cole
    Research
    Nature Genetics
    Volume: 41, P: 1282-1289

  • A dataset of coding variation, derived from exome sequencing of nearly one million individuals from a range of ancestries, provides insight into rare variants and could accelerate the discovery of disease-associated genes and advance precision medicine efforts.

    • Kathie Y. Sun
    • Xiaodong Bai
    • Suganthi Balasubramanian
    ResearchOpen Access
    Nature
    Volume: 631, P: 583-592

  • Expression of the Epstein–Barr virus protein LMP1 in B cells increases expression of—and promotes T cell responses to—tumour-associated antigens, delineating a mechanism of infection-induced anti-tumour immunity, which could inform immune-based approaches to cancer treatment.

    • Il-Kyu Choi
    • Zhe Wang
    • Baochun Zhang
    Research
    Nature
    Volume: 590, P: 157-162

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103

  • Heart failure is a complex syndrome that is associated with many different underlying risk factors. Here, to increase power, the authors jointly analyse cases of heart failure of different aetiologies in a genome-wide association study and identify 11 loci of which ten had not been previously reported.

    • Sonia Shah
    • Albert Henry
    • R. Thomas Lumbers
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12