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  • NFAT nuclear translocation has been shown to be required for CD8+ T cell cytokine production in response to viral infection. Here the authors show NFATc1 controls the cytotoxicity and metabolic switching of activated CD8+ T cells required for optimal response to bacteria and tumor cells.

    • Stefan Klein-Hessling
    • Khalid Muhammad
    • Edgar Serfling
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15