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Showing 1–2 of 2 results
Advanced filters: Author: Jessie C. Morrill Clear advanced filters
  • Melanocortin action is known to regulate body weight. Here the authors report that while inhibition of the hypothalamic melanocortin action leads to obesity in mice, chronic activation of melanocortin action is not sufficient to cause weight loss.

    • Hongli Li
    • Yuanzhong Xu
    • Qingchun Tong
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16
  • Leptin can rescue hyperglycemia in type 1 diabetes, but the underlying mechanisms for this effect are not clear. Here, the authors report that leptin action is mediated by inhibition of the heightened activity of arcuate GABA neurons in murine models of type 1 diabetes through restoring nutrient sensing.

    • Shengjie Fan
    • Yuanzhong Xu
    • Qingchun Tong
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15