Nature Search

Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV receptor.

Mayank Srivastava
Ying Zhang
W. Andy Tao
ResearchOpen Access04 Aug 2020
Nature Communications

Volume: 11, P: 1-10
Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth

Bispecific antibodies can have advantages compared to antibody cocktails. Here, the authors engineer and characterize two different approaches for generating bispecific SARS-CoV-2 specific antibodies and find that only one design increases antigen-binding and virus neutralizing activities.

Zhiqiang Ku
Xuping Xie
Zhiqiang An
ResearchOpen Access22 Sept 2022
Nature Communications

Volume: 13, P: 1-12
Slope stability considering multi-fissure seepage under rainfall conditions

Jianqing Jia
Chengxin Mao
Victor O. Tenorio
ResearchOpen Access22 May 2024
Scientific Reports

Volume: 14, P: 1-10
Surgery versus no surgery in platinum-sensitive relapsed ovarian cancer: final overall survival analysis of the SOC-1 randomized phase 3 trial

In a phase 3 randomized controlled trial comparing secondary cytoreduction plus chemotherapy versus chemotherapy alone in patients with relapsed ovarian cancer, the coprimary endpoint of overall survival was not statistically different, but in a prespecified sensitivity analysis adjusted for patients who underwent crossover surgery following tumor relapse, there was an increase in overall survival.

Rong Jiang
Yanling Feng
Rongyu Zang
Research01 Jun 2024
Nature Medicine

Volume: 30, P: 2181-2188
Temporospatial hierarchy and allele-specific expression of zygotic genome activation revealed by distant interspecific urochordate hybrids

Wei et al. report a unique interspecific ascidian hybrid system and single-cell RNA sequencing to reveal the temporal hierarchy, spatial heterogeneity, and allele-specific expression of zygotic genome activation in urochordates.

Jiankai Wei
Wei Zhang
Bo Dong
ResearchOpen Access16 Mar 2024
Nature Communications

Volume: 15, P: 1-11
Efficient intervention for pulmonary fibrosis via mitochondrial transfer promoted by mitochondrial biogenesis

Using healthy mitochondria to restore impaired mitochondrial homeostasis is a promising therapy for pulmonary fibrosis. Here the authors use joint-engineered mesenchymal stem cells for efficient mitochondrial delivery to injured lung cells, showing a successful mitigation of the disease.

Ting Huang
Ruyi Lin
Jianqing Gao
ResearchOpen Access18 Sept 2023
Nature Communications

Volume: 14, P: 1-15
Microvascular endothelial cells engulf myelin debris and promote macrophage recruitment and fibrosis after neural injury

Blood vessels help macrophage entry. Zhou et al. show that activated microvessels serve as critical portals for macrophage entry to boost inflammation after spinal cord injury.

Tian Zhou
Yiming Zheng
Yi Ren
Research21 Jan 2019
Nature Neuroscience

Volume: 22, P: 421-435
2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

Many cellular and virus messenger RNAs are methylated at the 2′-O positions of the 5′ guanosine cap. The role of 2′-O methylation in virus infection has been unclear. These authors show that this form of methylation enables several unrelated viruses to evade the antiviral effects of genes stimulated by type I interferon.

Stephane Daffis
Kristy J. Szretter
Michael S. Diamond
Research17 Nov 2010
Nature

Volume: 468, P: 452-456
Influencing electroclinical features and prognostic factors in patients with anti-NMDAR encephalitis: a cohort follow-up study in Chinese patients

Yingxin Wang
Ailiang Miao
Xiaoshan Wang
ResearchOpen Access01 Jul 2020
Scientific Reports

Volume: 10, P: 1-10
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

The Microarray Quality Control consortium pitted 36 teams against each other to evaluate methods for creating genomic classifiers, computational tools for interpreting gene expression profiles. The performance of the classifiers on blinded validation data—and metadata on the analytic methods—reveal the challenges facing the field.

Leming Shi
Gregory Campbell
Russell D Wolfinger
Research30 Jul 2010
Nature Biotechnology

Volume: 28, P: 827-838
A sequential re-opening of provinces for China’s zero-COVID policy

Cong Xu
Xiangrong Wang
Yanqing Hu
Correspondence13 Feb 2023
Nature Medicine

Volume: 29, P: 2977-2978
Whole-genome variants resource of 298 Saanen dairy goats

Kai Zhang
Jianqing Zhao
Hengbo Shi
ResearchOpen Access29 Mar 2025
Scientific Data

Volume: 12, P: 1-8
Soil microbial biodiversity supports the delivery of multiple ecosystem functions under elevated CO₂ and warming

Under elevated CO₂ and temperature conditions, agroecosystem stability is closely associated with soil fungal and nematode abundance during the rice and wheat growing season respectively, according to field data from a rice-wheat agroecosystem experiment in Jiangsu Province, China.

Jianqing Wang
Josep Peñuelas
Genxing Pan
ResearchOpen Access23 Oct 2024
Communications Earth & Environment

Volume: 5, P: 1-9
TNIP3 protects against pathological cardiac hypertrophy by stabilizing STAT1

Hongjie Shi
Yongjie Yu
Hongliang Li
ResearchOpen Access26 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-12
Nuclear FOXP3 inhibits tumor growth and induced apoptosis in hepatocellular carcinoma by targeting c-Myc

Zhongqin Gong
Hao Jia
George Gong Chen
ResearchOpen Access28 Oct 2020
Oncogenesis

Volume: 9, P: 1-11
HNF1B-mediated repression of SLUG is suppressed by EZH2 in aggressive prostate cancer

Jianqing Wang
Chenxi He
Fei Lan
ResearchOpen Access21 Oct 2019
Oncogene

Volume: 39, P: 1335-1346
LanCL1 protects prostate cancer cells from oxidative stress via suppression of JNK pathway

Jianqing Wang
Qianyi Xiao
Guanxiong Ding
ResearchOpen Access07 Feb 2018
Cell Death & Disease

Volume: 9, P: 1-12
Mitochondria dysfunction in Charcot Marie Tooth 2B Peripheral Sensory Neuropathy

The Rab7^V162M mutation associated with Charcot Marie Tooth 2B peripheral neuropathy causes mitochondrial fragmentation in patient-derived fibroblasts and primary cultured dorsal root ganglion sensory neurons from E18 mouse embryos.

Yingli Gu
Flora Guerra
Chengbiao Wu
ResearchOpen Access18 Jul 2022
Communications Biology

Volume: 5, P: 1-17
The biogeography of fungal communities in wetland sediments along the Changjiang River and other sites in China

Bing Wu
Jianqing Tian
Xingzhong Liu
Research28 Feb 2013
The ISME Journal

Volume: 7, P: 1299-1309
Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies

Chunyan Yi
Xiaoyu Sun
Bing Sun
ResearchOpen Access15 May 2020
Cellular & Molecular Immunology

Volume: 17, P: 621-630
Hymecromone: a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression

Shuai Yang
Yun Ling
Hongzhou Lu
ResearchOpen Access18 Mar 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-10

Search

Filter By:

Search

Quick links