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Flexible TAM requirement of TnpB enables efficient single-nucleotide editing with expanded targeting scope

Here the authors report that a thermophilic archaeal TnpB enables efficient gene editing in the natural host: they see that the TnpB has different TAM requirements for eliciting cell death and for facilitating gene editing. They show that TnpB can be harnessed for flexible single-nucleotide editing with templated repair.

Xu Feng
Ruyi Xu
Qunxin She
ResearchOpen Access24 Apr 2024
Nature Communications

Volume: 15, P: 1-14
Mining and expression analysis of color related genes in Bougainvillea glabra bracts based on transcriptome sequencing

Fei Wang
GuoQiong Yao
PeiYao Xin
ResearchOpen Access18 Oct 2024
Scientific Reports

Volume: 14, P: 1-21
Establishment of a recombinase polymerase amplification detection method for Puccinia striiformis f. sp. tritici

Yaoxia Liu
Jianyun Hao
Qiang Yao
ResearchOpen Access26 Sept 2023
Scientific Reports

Volume: 13, P: 1-10
Laser solid-phase synthesis of single-atom catalysts

Synthesis of Pt single atom catalysts is achieved by one-step laser irradiation of “isolated” H₂PtCl₆ precursor on graphene oxide, via filtration and freeze-drying sublimation, by simultaneous pyrolysis of the precursor and reduction of graphene oxide.

Yudong Peng
Jianyun Cao
Zhu Liu
ResearchOpen Access18 Aug 2021
Light: Science & Applications

Volume: 10, P: 1-14
Cold adaptation regulated by cryptic prophage excision in Shewanella oneidensis

Zhenshun Zeng
Xiaoxiao Liu
Xiaoxue Wang
ResearchOpen Access02 Aug 2016
The ISME Journal

Volume: 10, P: 2787-2800

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Flexible TAM requirement of TnpB enables efficient single-nucleotide editing with expanded targeting scope

Mining and expression analysis of color related genes in Bougainvillea glabra bracts based on transcriptome sequencing

Establishment of a recombinase polymerase amplification detection method for Puccinia striiformis f. sp. tritici

Laser solid-phase synthesis of single-atom catalysts

Cold adaptation regulated by cryptic prophage excision in Shewanella oneidensis

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Flexible TAM requirement of TnpB enables efficient single-nucleotide editing with expanded targeting scope

Mining and expression analysis of color related genes in Bougainvillea glabra bracts based on transcriptome sequencing

Establishment of a recombinase polymerase amplification detection method for Puccinia striiformis f. sp. tritici

Laser solid-phase synthesis of single-atom catalysts

Cold adaptation regulated by cryptic prophage excision in Shewanella oneidensis

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