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Showing 1–8 of 8 results
Advanced filters: Author: Jim Al-Khalili Clear advanced filters

  • In the midst of the COVID-19 pandemic, science is crucial to inform public policy. At the same time, mistrust of scientists and misinformation about scientific facts are rampant. Six scientists, actively involved in outreach, reflect on how to build a better understanding and trust of science.

    • Katherine Mack
    • Karl Kruszelnicki
    • Vlatko Vedral
    Reviews
    Nature Reviews Physics
    Volume: 2, P: 282-284

  • Jim Al-Khalili revisits Ibn al-Haytham's hugely influential study on its millennium.

    • Jim Al-Khalili
    Books & Arts
    Nature
    Volume: 518, P: 164-165

  • What were the chances that the conditions in the Universe would be just right for life?

    • Jim Al-Khalili
    Books & Arts
    Nature
    Volume: 444, P: 423-424

  • Proton transfer between DNA bases can lead to mutagenic tautomers, but as their lifetimes are thought to be much shorter than DNA separation times their role during the DNA replication cycle is often overlooked. Here, the authors model the separation of the DNA base pair guanine-cytosine using density functional theory and find increased stability of the tautomer when the DNA strands unzip as they enter a helicase enzyme, effectively trapping the tautomer population.

    • Louie Slocombe
    • Max Winokan
    • Marco Sacchi
    ResearchOpen Access
    Communications Chemistry
    Volume: 5, P: 1-9

  • The genetic stability of DNA suffers from proton transfer along the hydrogen bonds that can lead to tautomerisation, creating mutations. The authors theoretically examine the tautomerisation of the GuanineCytosine (G-C) nucleotide base-pair using an open quantum systems approach, finding that the contribution of quantum tunnelling to the reaction rate outweighs classical barrier-hopping.

    • Louie Slocombe
    • Marco Sacchi
    • Jim Al-Khalili
    ResearchOpen Access
    Communications Physics
    Volume: 5, P: 1-9