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Showing 101–122 of 122 results

Advanced filters: Author: Jimmy Lin Clear advanced filters

Nuclear topology modulates the mutational landscapes of cancer genomes

Genome-wide analyses of somatic mutations across six cancer types show that mutation frequencies differ between chromosomal regions located at the nuclear core versus the periphery, and thus mutational patterns are influenced by nuclear architecture.

Kyle S Smith
Lin L Liu
Subhajyoti De
Research02 Oct 2017
Nature Structural & Molecular Biology

Volume: 24, P: 1000-1006
Utilizing Multiple in Silico Analyses to Identify Putative Causal SCN5A Variants in Brugada Syndrome

Jyh-Ming Jimmy Juang
Tzu-Pin Lu
Jiunn-Lee Lin
ResearchOpen Access27 Jan 2014
Scientific Reports

Volume: 4, P: 1-9
Dietary glycaemic index and glycaemic load among Australian adults – results from the 2011–2012 Australian Health Survey

Jimmy Chun Yu Louie
Molly Jones
Jennie C. Brand-Miller
ResearchOpen Access06 Mar 2017
Scientific Reports

Volume: 7, P: 1-8
Author Correction: CMR-derived ECVs vary with myocardial region and associate with the regional wall thickness

Mao-Yuan Su
Kuei-Yuan Hou
Yeun-Chung Chang
Amendments and CorrectionsOpen Access09 Apr 2021
Scientific Reports

Volume: 11, P: 1
Quantum simulation of preferred tautomeric state prediction

Yu Shee
Tzu-Lan Yeh
Min-Hsiu Hsieh
ResearchOpen Access16 Oct 2023
npj Quantum Information

Volume: 9, P: 1-12
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates

Azra Ajkunic
Erolcan Sayar
Michael C. Haffner
ResearchOpen Access17 May 2024
npj Precision Oncology

Volume: 8, P: 1-9
In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer

Kornelia Polyak, Franziska Michor and colleagues report a novel method, STAR-FISH, for combined in situ single-cell analysis of point mutations and copy number alterations in archived tissue samples. They apply STAR-FISH to clinically relevant PIK3CA mutations and HER2 amplifications and observe associations between intratumoral diversity and clinical outcome.

Michalina Janiszewska
Lin Liu
Kornelia Polyak
Research24 Aug 2015
Nature Genetics

Volume: 47, P: 1212-1219
Correction: Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Daniel Doheny
Sherona Sirkisoon
Hui-Wen Lo
Amendments and Corrections27 Apr 2024
Oncogene

Volume: 43, P: 1811
The mathematics of cancer: integrating quantitative models

This Review discusses mathematical modelling approaches in cancer research. These models can complement experimental and clinical studies, but can also challenge current paradigms, redefine our understanding of mechanisms driving tumorigenesis and shape future research.

Philipp M. Altrock
Lin L. Liu
Franziska Michor
Reviews24 Nov 2015
Nature Reviews Cancer

Volume: 15, P: 730-745
DNA methylation levels of RELN promoter region in ultra-high risk, first episode and chronic schizophrenia cohorts of schizophrenia

Sok-Hong Kho
Jie Yin Yee
Judy Chia Ghee Sng
ResearchOpen Access10 Oct 2022
Schizophrenia

Volume: 8, P: 1-9
Derive and conquer: sourcing and differentiating stem cells for therapeutic applications

The success of stem-cell-based therapies depends on finding reliable sources of multipotent and pluripotent cells, and the ability to generate desired derivatives. Here, the authors discuss problems associated with the sourcing of human embyonic stem cells and discuss the current status of stem-cell differentiation technology.

Irina Klimanskaya
Nadia Rosenthal
Robert Lanza
Reviews01 Feb 2008
Nature Reviews Drug Discovery

Volume: 7, P: 131-142
TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Sherona R. Sirkisoon
Richard L. Carpenter
Hui-Wen Lo
Research28 Aug 2019
Oncogene

Volume: 39, P: 64-78
Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis

Daniel Doheny
Sherona Sirkisoon
Hui-Wen Lo
Research14 Sept 2020
Oncogene

Volume: 39, P: 6589-6605
A polygenic resilience score moderates the genetic risk for schizophrenia

Jonathan L. Hess
Daniel S. Tylee
Stephen J. Glatt
ResearchOpen Access06 Sept 2019
Molecular Psychiatry

Volume: 26, P: 800-815
Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment

Sherona R. Sirkisoon
Richard L. Carpenter
Hui-Wen Lo
Amendments and Corrections02 Mar 2021
Oncogene

Volume: 40, P: 2338
Progressive Decline in Hippocampal CA1 Volume in Individuals at Ultra-High-Risk for Psychosis Who Do Not Remit: Findings from the Longitudinal Youth at Risk Study

New Fei Ho
Daphne J Holt
Juan Zhou
ResearchOpen Access12 Jan 2017
Neuropsychopharmacology

Volume: 42, P: 1361-1370
Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest

Prashant Rai
Fang He
Vincent T.K. Chow
ResearchOpen Access30 Mar 2016
Scientific Reports

Volume: 6, P: 1-12
Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11

Thomas A. Ravenscroft
Jennifer B. Phillips
Hugo J. Bellen
Research10 Jun 2021
Genetics in Medicine

Volume: 23, P: 1889-1900
Author Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells

Nouar Qutob
Ikuo Masuho
Yardena Samuels
Amendments and CorrectionsOpen Access09 Mar 2019
Scientific Reports

Volume: 9, P: 1-2
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Parvalbumin Cell Ablation of NMDA-R1 Causes Increased Resting Network Excitability with Associated Social and Self-Care Deficits

Eddie N Billingslea
Valerie M Tatard-Leitman
Steven J Siegel
Research14 Feb 2014
Neuropsychopharmacology

Volume: 39, P: 1603-1613

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