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Cell Death Discovery (2)

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BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis

BMP9 inhibits cellular senescence by activation of Smad1, which suppresses the transcription of Stat1, resulting in decreased P21 expression and SASPs production in osteoblast. The anti-aging effect of BMP9 is benefit to improving age-related osteoporosis.

Jing-zun Xu
Yan-man Zhou
Jian-min Liu
ResearchOpen Access06 May 2022
Cell Death Discovery

Volume: 8, P: 1-14
Correction to: BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis

Jing-zun Xu
Yan-man Zhou
Jian-min Liu
Amendments and CorrectionsOpen Access22 Jul 2022
Cell Death Discovery

Volume: 8, P: 1-2

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BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis

Correction to: BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis

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