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Showing 1–7 of 7 results

Advanced filters: Author: Jinsan Zhang Clear advanced filters

The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome

AMPK and Parkin keep the necrosome in check. Lee et al. show that AMPK activates Parkin and prevents RIPK1−RIPK3 complex formation by promoting RIPK3 ubiquitination, thereby negatively regulating necroptosis, inflammation and tumour initiation.

Seung Baek Lee
Jung Jin Kim
Zhenkun Lou
Research29 Jul 2019
Nature Cell Biology

Volume: 21, P: 940-951
A ribosomal gene panel predicting a novel synthetic lethality in non-BRCAness tumors

Chao Zhang
Qiang Guo
Jin-San Zhang
ResearchOpen Access10 May 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-17
Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab

Dawei Wang
Qingqing Xu
Huiqing Yuan
ResearchOpen Access15 Jan 2019
Oncogene

Volume: 38, P: 3458-3474
FGF10 mitigates doxorubicin-induced myocardial toxicity in mice via activation of FGFR2b/PHLDA1/AKT axis

De-pu Zhou
Lian-cheng Deng
Jin-San Zhang
ResearchOpen Access24 May 2023
Acta Pharmacologica Sinica

Volume: 44, P: 2004-2018
Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer

J-S Zhang
A Koenig
D D Billadeau
Research28 Mar 2011
Oncogene

Volume: 30, P: 3705-3715
ZNF185, an actin–cytoskeleton-associated growth inhibitory LIM protein in prostate cancer

J-S Zhang
A Gong
C Y F Young
Research26 Jun 2006
Oncogene

Volume: 26, P: 111-122
Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells

J-S Zhang
M Herreros-Villanueva
D D Billadeau
ResearchOpen Access27 Mar 2014
Cell Death & Disease

Volume: 5, P: e1142