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Trim15 stabilizes VDAC3 via ubiquitination to suppress autophagy and enhance chemosensitivity in hypopharyngeal squamous cell carcinoma

Guangyi Wang
Yibang Shen
Jisheng Zhang
ResearchOpen Access30 Jan 2026
Cell Death Discovery

Volume: 12, P: 1-12
Single-cell transcriptomics reveals BMP4-BMPR2 signaling promotes radiation resistance in hematopoietic stem cells following injury

The heterogeneity of HSPCs in response to IR stress remains poorly characterized. Here, the authors provide insights into the molecular intricacies of IR-induced BM injury and reveal the roles of BMP4-BMPR2 signaling in radiation resistance of HSCs.

Yanhua Li
Yunxing Li
Gangqiao Zhou
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-18
Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

Here, the authors use multi-omic data to reveal how genetic and epigenetic variation affects gene expression in two pig breeds. The findings highlight strong tissue-specific regulation and identify genes with allele-specific expression.

Jianping Quan
Ming Yang
Zhenfang Wu
ResearchOpen Access03 Jul 2024
Nature Communications

Volume: 15, P: 1-18
Intradiscal cement leakage (ICL) increases the stress on adjacent vertebrae after kyphoplasty for osteoporotic vertebra compression fracture (OVCF): a finite-element study

Hai Meng
Qiujun Li
Qi Fei
ResearchOpen Access25 Sept 2023
Scientific Reports

Volume: 13, P: 1-9
Subgenome parallel selection is associated with morphotype diversification and convergent crop domestication in Brassica rapa and Brassica oleracea

Xiaowu Wang, Jian Wu, Guusje Bonnema and colleagues report resequencing and subgenome selection analysis of 199 Brassica rapa and 119 Brassica oleracea accessions representing diverse morphotypes. They identify 4 subgenome loci with evidence of parallel selection among subgenomes and 15 subgenome loci with evidence of parallel selection between species.

Feng Cheng
Rifei Sun
Xiaowu Wang
Research15 Aug 2016
Nature Genetics

Volume: 48, P: 1218-1224
hapln1a⁺ cells guide coronary growth during heart morphogenesis and regeneration

The guidance cues critical for coronary growth remain unclear. Here, Sun et al. reveal the requirement of hapln1a⁺ cells and serpine1 to establish a microenvironment for guided coronary growth during zebrafish heart morphogenesis and regeneration.

Jisheng Sun
Elizabeth A. Peterson
Jinhu Wang
ResearchOpen Access13 Jun 2023
Nature Communications

Volume: 14, P: 1-16
Identification of drought-responsive microRNAs and their targets in Ammopiptanthus mongolicus by using high-throughput sequencing

Fei Gao
Ning Wang
Yijun Zhou
ResearchOpen Access04 Oct 2016
Scientific Reports

Volume: 6, P: 1-16
Hyperoside pre-treatment prevents glomerular basement membrane damage in diabetic nephropathy by inhibiting podocyte heparanase expression

Xiaofei An
Lin Zhang
Jinan Zhang
ResearchOpen Access25 Jul 2017
Scientific Reports

Volume: 7, P: 1-12
Stabilized β-catenin promotes hepatocyte proliferation and inhibits TNFα-induced apoptosis

Xian-Zhang Shang
Haizhen Zhu
Chen Liu
Research26 Jan 2004
Laboratory Investigation

Volume: 84, P: 332-341

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Trim15 stabilizes VDAC3 via ubiquitination to suppress autophagy and enhance chemosensitivity in hypopharyngeal squamous cell carcinoma

Single-cell transcriptomics reveals BMP4-BMPR2 signaling promotes radiation resistance in hematopoietic stem cells following injury

Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

Intradiscal cement leakage (ICL) increases the stress on adjacent vertebrae after kyphoplasty for osteoporotic vertebra compression fracture (OVCF): a finite-element study

Subgenome parallel selection is associated with morphotype diversification and convergent crop domestication in Brassica rapa and Brassica oleracea

hapln1a⁺ cells guide coronary growth during heart morphogenesis and regeneration

Identification of drought-responsive microRNAs and their targets in Ammopiptanthus mongolicus by using high-throughput sequencing

Hyperoside pre-treatment prevents glomerular basement membrane damage in diabetic nephropathy by inhibiting podocyte heparanase expression

Stabilized β-catenin promotes hepatocyte proliferation and inhibits TNFα-induced apoptosis

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