Nature Search

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Publisher Correction: Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells

Luiz Carlos Caires-Júnior
Ernesto Goulart
Mayana Zatz
Amendments and CorrectionsOpen Access13 Mar 2018
Nature Communications

Volume: 9, P: 1-2
Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in Portugal

An analysis of viral genomes and epidemiological data from the 2022 mpox outbreak in Portugal sheds light on the heterogeneity of early transmission events, with national and international linkages.

Vítor Borges
Mariana Perez Duque
João Paulo Gomes
ResearchOpen Access11 Sept 2023
Nature Medicine

Volume: 29, P: 2509-2517
Fermentability coefficient of tropical forages and fermentative profile and in vitro degradability of silages

Wagner Sousa Alves
Gabriel Ferreira de Lima Cruz
Karina Guimarães Ribeiro
ResearchOpen Access25 Aug 2025
Scientific Reports

Volume: 15, P: 1-14
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Genomic history of coastal societies from eastern South America

The authors report genome-wide data from 34 ancient individuals spanning the Holocene, from what is now Brazil, illuminating connections and disjoints between Sambaqui shellmound societies and preceding and later peoples.

Tiago Ferraz
Ximena Suarez Villagran
Cosimo Posth
ResearchOpen Access31 Jul 2023
Nature Ecology & Evolution

Volume: 7, P: 1315-1330
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells

Zika virus (ZIKV) infection can cause congenital Zika syndrome (CZS), but the underlying mechanisms are poorly understood. Here, the authors generate neural progenitor cells from dizygotic twins with a discordant phenotype regarding CZS and study their response to ZIKV infection.

Luiz Carlos Caires-Júnior
Ernesto Goulart
Mayana Zatz
ResearchOpen Access02 Feb 2018
Nature Communications

Volume: 9, P: 1-11
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

A high-resolution, global atlas of mortality of children under five years of age between 2000 and 2017 highlights subnational geographical inequalities in the distribution, rates and absolute counts of child deaths by age.

Roy Burstein
Nathaniel J. Henry
Simon I. Hay
ResearchOpen Access16 Oct 2019
Nature

Volume: 574, P: 353-358
Variation in wood density across South American tropical forests

Wood density is a key control on tree biomass, and understanding its spatial variation improves estimates of forest carbon stock. Sullivan et al. measure >900 forest plots to quantify wood density and produce high resolution maps of its variation across South American tropical forests.

Martin J. P. Sullivan
Oliver L. Phillips
Joeri A. Zwerts
ResearchOpen Access10 Mar 2025
Nature Communications

Volume: 16, P: 1-12
Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil

The COVID-19 pandemic in Brazil is assessed using phylogenetic and phylogeographic analysis.

Marta Giovanetti
Svetoslav Nanev Slavov
Dimas Tadeu Covas
ResearchOpen Access18 Aug 2022
Nature Microbiology

Volume: 7, P: 1490-1500
Immunogenicity and safety of CoronaVac vaccine in children and adolescents (Immunita-002, Brazil): A phase IV six-month follow up

Camila Amormino Corsini
Priscila Fernanda da Silva Martins
Rafaella Fortini Queiroz e Grenfell
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Multi-country and intersectoral assessment of cluster congruence between pipelines for genomics surveillance of foodborne pathogens

In the era of global foodborne pathogens’ genomic surveillance, this study shows that large-scale inter-laboratory comparisons are needed and feasible, opening good perspectives for efficient and cooperative One Health outbreak investigations.

Verónica Mixão
Miguel Pinto
Vítor Borges
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-27
IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expression

Moreno-Loaiza et al. found that interleukin-1β, acting upon cardiac resident macrophages, promotes atrial fibrillation in mice, and this mechanism may represent a common pathway connecting various risk factors to this arrhythmia.

Oscar Moreno-Loaiza
Vinicius Cardoso Soares
Emiliano Medei
Research06 Feb 2025
Nature Cardiovascular Research

Volume: 4, P: 312-329
Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus

Analysis of the first sequences from the 2022 multi-country outbreak of monkeypox virus shows relatedness and substantial divergence from a 2018–2019 outbreak, suggesting rapid virus evolution with possible implications for human-to-human transmission.

Joana Isidro
Vítor Borges
João Paulo Gomes
ResearchOpen Access24 Jun 2022
Nature Medicine

Volume: 28, P: 1569-1572
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
Addendum: Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus

Joana Isidro
Vítor Borges
João Paulo Gomes
Amendments and CorrectionsOpen Access21 Sept 2022
Nature Medicine

Volume: 28, P: 2220-2221
Primary results of the brazilian registry of atherothrombotic disease (NEAT)

Pedro G. M. de Barros e Silva
Charlene Troiani do Nascimento
Mauricio Antonio Pompilio
ResearchOpen Access20 Feb 2024
Scientific Reports

Volume: 14, P: 1-10
Rhesus macaques self-curing from a schistosome infection can display complete immunity to challenge

To date there is only one single drug with modest efficacy and no vaccine available to protect from schistosomiasis. Here, Amaral et al. characterize the self-cure process of rhesus macaques following primary infection and secondary challenge with Schistosoma mansoni to inform future vaccine development studies.

Murilo Sena Amaral
Daisy Woellner Santos
Sergio Verjovski-Almeida
ResearchOpen Access26 Oct 2021
Nature Communications

Volume: 12, P: 1-17
Promotion of neutralizing antibody-independent immunity to wild-type and SARS-CoV-2 variants of concern using an RBD-Nucleocapsid fusion protein

Protection against SARS-CoV-2 infection involves T cell and B cell responses but only studying one or the other has proved difficult. Here the authors immunise with a fusion protein construct of N and RBD proteins from SARS-CoV-2 and find that this promotes protection in animal models preferentially via T cells.

Julia T. Castro
Patrick Azevedo
Ricardo T. Gazzinelli
ResearchOpen Access17 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Detection of germline variants in Brazilian breast cancer patients using multigene panel testing

Rodrigo Santa Cruz Guindalini
Danilo Vilela Viana
Maria Aparecida Azevedo Koike Folgueira
ResearchOpen Access09 Mar 2022
Scientific Reports

Volume: 12, P: 1-12
SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal

Borges et al. study the dynamics of SARS-CoV-2 in Portugal during 2020. The authors use phylodynamic modelling to infer patterns of SARS-CoV-2 introduction into Portugal and its subsequent spread, providing a comprehensive genomic epidemiology study of the early SARS-CoV-2 epidemic in Portugal.

Vítor Borges
Joana Isidro
João Paulo Gomes
ResearchOpen Access28 Jan 2022
Communications Medicine

Volume: 2, P: 1-11
Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil

Chikungunya virus is endemic in Brazil and cases have been rapidly increasing in recent years. Here, the authors describe the expansion of a genomic surveillance program across the country allowing them to characterise the emergence and dispersal of two distinct subclades mainly seeded from the north eastern region.

Joilson Xavier
Luiz Carlos Junior Alcantara
Marta Giovanetti
ResearchOpen Access21 Jul 2023
Nature Communications

Volume: 14, P: 1-12
Contrast phase recognition in liver computer tomography using deep learning

Bruno Aragão Rocha
Lorena Carneiro Ferreira
Suzane Kioko Ono
ResearchOpen Access24 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
Global genomic methylation related to the degree of parasitism in cattle

Ricardo Velludo Gomes de Soutello
Maria Gabriela Fontanetti Rodrigues
Ester Silveira Ramos
ResearchOpen Access28 Oct 2022
Scientific Reports

Volume: 12, P: 1-8
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil

Emerging variants of SARS-CoV-2 raise concerns about vaccine efficiency. Here, the authors present a post-hoc analysis for the ChAdOx1 nCoV-19 (AZD1222) vaccine trial in Brazil and provide efficacy against symptomatic COVID-19 caused by the Zeta (P.2) and other variants.

Sue Ann Costa Clemens
Pedro M. Folegatti
Rafael Zimmer
ResearchOpen Access06 Oct 2021
Nature Communications

Volume: 12, P: 1-10
Biomass production and silage quality of ensiled BRS Capiaçu elephant grass at different regrowth ages and residue heights

Daiana Lopes Lelis
Domingos Sávio Campos Paciullo
Fernanda Helena Martins Chizzotti
ResearchOpen Access01 Feb 2025
Scientific Reports

Volume: 15, P: 1-10
Current management of inherited retinal degenerations in Portugal (IRD-PT survey)

João Pedro Marques
Nuno Ferreira
Eduardo Silva
ResearchOpen Access14 Sept 2024
Scientific Reports

Volume: 14, P: 1-10
Magnetic resonance imaging texture analysis to differentiate ameloblastoma from odontogenic keratocyst

João Pedro Perez Gomes
Celso Massahiro Ogawa
Andre Luiz Ferreira Costa
ResearchOpen Access21 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
This hot AI summer will impact Brazil’s democracy

The current debate surrounding the use and regulation of artificial intelligence (AI) in Brazil has social and political implications. We summarize these discussions, advocate for balance in the current debate around AI and fake news, and caution against preemptive AI regulation.

Cristina Godoy B. de Oliveira
Fabio G. Cozman
João Paulo C. Veiga
Comments & Opinion20 Nov 2023
Nature Human Behaviour

Volume: 7, P: 1842-1844
Seroprevalence of hepatitis E virus in risk populations and blood donors in a referral hospital in the south of Brazil

Marisa Boff Costa
Michele Soares Gomes Gouvêa
Mário Reis Álvares-da-Silva
ResearchOpen Access16 Mar 2021
Scientific Reports

Volume: 11, P: 1-5
Effects of exogenous protease addition on fermentation and nutritive value of rehydrated corn and sorghum grains silages

João Paulo Santos Roseira
Odilon Gomes Pereira
Karina Guimarães Ribeiro
ResearchOpen Access05 May 2023
Scientific Reports

Volume: 13, P: 1-9
A role of asynchrony of seasons in explaining genetic differentiation in a Neotropical toad

Maria Tereza C. Thomé
Bryan C. Carstens
Célio F. B. Haddad
Research24 Jul 2021
Heredity

Volume: 127, P: 363-372
A nationwide collapse of a priority grassland bird related to livestock conversion and intensification

João Paulo Silva
Ana Teresa Marques
João Gameiro
ResearchOpen Access29 Jun 2023
Scientific Reports

Volume: 13, P: 1-10
Mapping routine measles vaccination in low- and middle-income countries

Although progress in the coverage of routine measles vaccination in children in low- and middle-income countries was made during 2000–2019, many countries remain far from the goal of 80% coverage in all districts by 2019.

Alyssa N. Sbarra
Sam Rolfe
Jonathan F. Mosser
ResearchOpen Access16 Dec 2020
Nature

Volume: 589, P: 415-419
Characterization of pharmacogenetic markers related to Acute Lymphoblastic Leukemia toxicity in Amazonian native Americans population

Darlen Cardoso de Carvalho
Alayde Vieira Wanderley
Ney Pereira Carneiro dos Santos
ResearchOpen Access24 Jun 2020
Scientific Reports

Volume: 10, P: 1-9
Aerobic exercise training mitigates tumor growth and cancer-induced splenomegaly through modulation of non-platelet platelet factor 4 expression

Gabriel C. Tobias
João L. P. Gomes
Patricia C. Brum
ResearchOpen Access11 Dec 2023
Scientific Reports

Volume: 13, P: 1-15
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Genome-scale analysis of the non-cultivable Treponema pallidum reveals extensive within-patient genetic variation

Direct genome sequencing from clinical samples shows that Treponema pallidum experiences diversification during host infection.

Miguel Pinto
Vítor Borges
João Paulo Gomes
Research17 Oct 2016
Nature Microbiology

Volume: 2, P: 1-11
Molecular identification of whole squids and calamari at fairs and markets in regions of Latin America

Bianca Lima Paiva
Alan Erik Souza Rodrigues
João Bráullio de Luna Sales
ResearchOpen Access03 Dec 2024
Scientific Reports

Volume: 14, P: 1-12
Selective signatures and high genome-wide diversity in traditional Brazilian manioc (Manihot esculenta Crantz) varieties

Alessandro Alves-Pereira
Maria Imaculada Zucchi
Anete Pereira de Souza
ResearchOpen Access24 Jan 2022
Scientific Reports

Volume: 12, P: 1-14
Observation of electroweak production of two jets and a Z-boson pair

The ATLAS Collaboration reports the observation of the electroweak production of two jets and a Z-boson pair. This process is related to vector-boson scattering and allows the nature of electroweak symmetry breaking to be probed.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access09 Feb 2023
Nature Physics

Volume: 19, P: 237-253
1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors

Maurício T. Tavares
Arne Krüger
Roberto Parise-Filho
ResearchOpen Access29 Nov 2023
Scientific Reports

Volume: 13, P: 1-20
Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Clara Grilo
Tomé Neves
Eric Guinard
ResearchOpen Access31 Mar 2025
Scientific Data

Volume: 12, P: 1-14
Dendritic cells and regulatory T cells expressing CCR4 provide resistance to coxsackievirus B5-induced pancreatitis

Marcela C. S. Françozo
Frederico R. C. Costa
Renata Sesti-Costa
ResearchOpen Access14 Oct 2019
Scientific Reports

Volume: 9, P: 1-11
Test of the universality of τ and μ lepton couplings in W-boson decays with the ATLAS detector

The ATLAS Collaboration reports a measurement of the ratio of the decay rates of W bosons to τ leptons and muons, in agreement with universal lepton couplings as postulated in the standard model of particle physics.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access05 Jul 2021
Nature Physics

Volume: 17, P: 813-818
Search for charged-lepton-flavour violation in Z-boson decays with the ATLAS detector

The ATLAS experiment at the Large Hadron Collider reports a search for charged-lepton-flavour violation in decays of Z bosons into a τ lepton and an electron or muon of opposite charge.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access01 Jul 2021
Nature Physics

Volume: 17, P: 819-825
Dietary caloric input and tumor growth accelerate senescence and modulate liver and adipose tissue crosstalk

Physiological responses induced by different dietary regimens on the senescence process and, consequently, on the biology of tissues, such as WAT and liver, during tumor growth.

José Xavier do Nascimento Júnior
Júlia da Conceição Gomes
Patricia Zancan
ResearchOpen Access07 Jan 2025
Communications Biology

Volume: 8, P: 1-16
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308
Potential and limitations of machine meta-learning (ensemble) methods for predicting COVID-19 mortality in a large inhospital Brazilian dataset

Bruno Barbosa Miranda de Paiva
Polianna Delfino Pereira
Milena Soriano Marcolino
ResearchOpen Access01 Mar 2023
Scientific Reports

Volume: 13, P: 1-18

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