The development of fully defined culture conditions for human embryonic stem cells (hESCs) should enhance experimental reproducibility, reduce unwanted contaminants and facilitate scale-up production. Melkoumian et al. show that a substrate made of peptides derived from extracellular matrix proteins supports long-term culture of hESCs and differentiation to cardiomyocytes.
- Zara Melkoumian
- Jennifer L Weber
- Ralph Brandenberger
