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Showing 1–2 of 2 results
Advanced filters: Author: Joel van Roon Clear advanced filters

  • Tertiary lymphoid structures play important roles during homeostatic but also immunopathological conditions including autoimmune disorders. Here the authors integrate single cell sequencing with spatial proteomics and transcriptomics to define a cellular and spatial map of tertiary lymphoid structures in salivary glands of patients with Sjogren’s syndrome.

    • Saba Nayar
    • Jason D. Turner
    • Francesca Barone
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • Immunopathology in autoimmune diseases is promoted by complex interactions between many types of immune cells, and adequate disease inhibition relies on targeting molecules that orchestrate these interactions. One such molecule, IL-7, has well-known effects on lymphoid cells, but could this cytokine also affect innate immune cells to induce immunopathology?

    • Anneline C. Hinrichs
    • Joel A. G. van Roon
    News & Views
    Nature Reviews Rheumatology
    Volume: 15, P: 640-642