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Showing 1–6 of 6 results

Advanced filters: Author: Johannes M.F.G. Aerts Clear advanced filters

Velaglucerase alfa

Johannes M. F. G. Aerts
Uma Yasothan
Peter Kirkpatrick
Comments & Opinion29 Oct 2010
Nature Reviews Drug Discovery

Volume: 9, P: 837-838
Ultrasensitive in situ visualization of active glucocerebrosidase molecules

Fluorescent high-affinity activity-based probes used to monitor the activity and presence of active glucocerebrosidase in vitro and in vivo help in understanding Gaucher disease and its treatment with pharmacological chaperones.

Martin D Witte
Wouter W Kallemeijn
Johannes M F G Aerts
Research31 Oct 2010
Nature Chemical Biology

Volume: 6, P: 907-913
Activity-based probes for functional interrogation of retaining β-glucuronidases

Synthesis and application of activity-based probes based on cyclophellitol enabled the cellular profiling of β-glucuronidase activity and revealed an unexpected feature of endo-acting heparanase processing.

Liang Wu
Jianbing Jiang
Gideon J Davies
Research05 Jun 2017
Nature Chemical Biology

Volume: 13, P: 867-873
Is it Fabry disease?

Raphael Schiffmann
Maria Fuller
Johannes M.F.G. Aerts
Reviews19 May 2016
Genetics in Medicine

Volume: 18, P: 1181-1185
A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals

Michael D. Rugen
Mathieu M. J. L. Vernet
Robert A. Field
ResearchOpen Access06 Nov 2018
Scientific Reports

Volume: 8, P: 1-12
Ethnic differences in metabolite signatures and type 2 diabetes: a nested case–control analysis among people of South Asian, African and European origin

Irene G. M. van Valkengoed
Carmen Argmann
Riekelt H. Houtkooper
ResearchOpen Access19 Dec 2017
Nutrition & Diabetes

Volume: 7, P: 1-8