Li et al. produce a dengue virus (DENV)-derived defective interfering particle (DIP) production cell line that can stably produce infectious virusfree DIPs. The DENV DIPs produced from this system can potently inhibit replication of all DENV serotypes in cells and have the potential to be repurposed to make antiviral DIPs for other RNA viruses.
- Dongsheng Li
- Min-Hsuan Lin
- David Harrich
