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Showing 1–3 of 3 results
Advanced filters: Author: John C. Panepinto Clear advanced filters

  • The fungal pathogen Cryptococcus neoformans can adapt to mammalian core body temperature. Here, Bloom et al. show that Ccr4-mediated decay of ribosomal protein mRNAs is important for thermotolerance and immune evasion by promoting masking of cell wall glucans.

    • Amanda L. M. Bloom
    • Richard M. Jin
    • John C. Panepinto
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13

  • Sickle cell disease includes genetic conditions that are caused by mutations in one of the genes encoding haemoglobin. Mutant haemoglobin molecules can polymerize, causing the red blood cells to acquire a characteristic crescent shape that gives the disease its name.

    • Gregory J. Kato
    • Frédéric B. Piel
    • Elliott P. Vichinsky
    Reviews
    Nature Reviews Disease Primers
    Volume: 4, P: 1-22