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Showing 1–2 of 2 results
Advanced filters: Author: John J. Ponessa Clear advanced filters

  • P53 is a well-known tumour suppressor, however its role in intestinal type 2 immunity is currently unclear. Here authors report that during parasitic infections, p53 triggers tuft cell Ca2+ influx and IL-25 release, and shows a regulatory role for p53 in intestinal type 2 immunity via transcriptional regulation of the Lrmp gene.

    • Chun-Yuan Chang
    • Jianming Wang
    • Wenwei Hu
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13