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Showing 101–150 of 155 results

Advanced filters: Author: John Magee Clear advanced filters

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli
Massimo Bogliolo
Paolo Peterlongo
ResearchOpen Access01 Nov 2019
npj Breast Cancer

Volume: 5, P: 1-14
Nuclear-driven production of renewable fuel additives from waste organics

A current trend towards the sustainable production of valuable chemicals consists in coupling nuclear energy with the chemical industry. Here, the authors propose to use γ radiation to transform glycerol (a waste product of biorefineries) into high-value solketal.

Arran George Plant
Bor Kos
Malcolm John Joyce
ResearchOpen Access17 Sept 2021
Communications Chemistry

Volume: 4, P: 1-11
Liquid-liquid phase separation reduces radiative absorption by aged black carbon aerosols

Redistribution of black carbon from the inorganic core to the organic coating of aged aerosols due to liquid-liquid phase separation can reduce radiative absorption by up to 34%, according to field observations and laboratory experiments.

Jian Zhang
Yuanyuan Wang
Weijun Li
ResearchOpen Access02 Jun 2022
Communications Earth & Environment

Volume: 3, P: 1-9
A kilonova as the electromagnetic counterpart to a gravitational-wave source

Observations and modelling of an optical transient counterpart to a gravitational-wave event and γ-ray burst reveal that neutron-star mergers produce gravitational waves and radioactively powered kilonovae, and are a source of heavy elements.

S. J. Smartt
T.-W. Chen
O. Yaron
Research16 Oct 2017
Nature

Volume: 551, P: 75-79
Genomics, drug approval, and optimal treatment duration

2013 saw much progress in breast cancer research. Advances in high-throughput technologies continue to refine our knowledge of the molecular biology of breast cancer, and are beginning to give insight into cancer evolution, drug resistance, and how to deploy precision therapeutics.

Adrian V. Lee
Nancy E. Davidson
News & Views14 Jan 2014
Nature Reviews Clinical Oncology

Volume: 11, P: 71-72
A HUPO test sample study reveals common problems in mass spectrometry–based proteomics

A multilaboratory analysis characterized the ability of 27 different labs to identify 20 proteins at equimolar concentrations in a highly purified test sample mixture using mass spectrometry. The results show that while the technology is reproducible, many common experimental problems arise, and improved search engines and databases are still needed.

Alexander W Bell
Eric W Deutsch
Juan Antonio Vizcaíno
Research17 May 2009
Nature Methods

Volume: 6, P: 423-430
A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Welm and colleagues present a biobank of human-derived xenografts and organoids and demonstrate its value for high-throughput drug screening and applied precision medicine.

Katrin P. Guillen
Maihi Fujita
Alana L. Welm
ResearchOpen Access24 Feb 2022
Nature Cancer

Volume: 3, P: 232-250
Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
Amendments and CorrectionsOpen Access15 Feb 2019
Nature Communications

Volume: 10, P: 1-4
Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
Amendments and CorrectionsOpen Access02 May 2019
Nature Communications

Volume: 10, P: 1-4
Ras proteins: different signals from different locations

John F. Hancock
Reviews01 May 2003
Nature Reviews Molecular Cell Biology

Volume: 4, P: 373-385
Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase

Charles E Ducker
Erin M Stettler
Charles D Smith
Research18 Oct 2004
Oncogene

Volume: 23, P: 9230-9237
Inhibition of crystallin expression and induction of apoptosis by lens-specific E1A expression in transgenic mice

Qin Chen
John D Ash
Paul A Overbeek
Research18 Feb 2002
Oncogene

Volume: 21, P: 1028-1037
Polymorphisms in NR5A2, gene encoding liver receptor homolog-1 are associated with preterm birth

Dinushan C. Kaluarachchi
Allison M. Momany
Jeffrey C. Murray
Research13 Jan 2016
Pediatric Research

Volume: 79, P: 776-780
A gravitational-wave standard siren measurement of the Hubble constant

The astronomical event GW170817, detected in gravitational and electromagnetic waves, is used to determine the expansion rate of the Universe, which is consistent with and independent of existing measurements.

B. P. Abbott
R. Abbott
M. Serra-Ricart
Research16 Oct 2017
Nature

Volume: 551, P: 85-88
Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

The risk of germline copy number variants (CNVs) in BRCA1 and BRCA2 pathogenic variant carriers in breast cancer is assessed, with CNVs overlapping SULT1A1 decreasing breast cancer risk in BRCA1 carriers.

Christopher Hakkaart
John F. Pearson
Logan C. Walker
ResearchOpen Access06 Oct 2022
Communications Biology

Volume: 5, P: 1-15
Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation

Vilma Dembitz
Hannah Lawson
Paolo Gallipoli
ResearchOpen Access26 Aug 2024
Leukemia

Volume: 38, P: 2395-2409
Man, myth, geologist

Charles Darwin became the founder and mythic hero of modern evolutionary biology with the publication of his work On the Origin of Species 150 years ago. The book bears the signature of a geological thinker who had turned to a faster-moving discipline.

Mott T. Greene
Comments & Opinion01 Oct 2009
Nature Geoscience

Volume: 2, P: 666-667
Prenatal Glucocorticoid Induced Fetal and Postnatal Growth Restriction is Mediated by Obese Gene (OB) or Leptin Receptors † 1559

Saroj K Parida
Nicole K MacLennan
Sherin U Devaskar
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 266
Maternal and Fetal Leptin Correlate with Fetal Growth in Preeclampsia.† 1519

Carol H Gilmour
Thelma E Patrick
James M Roberts
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 260
Obese Gene (Leptin) Receptors are Widely Distributed in Embryonic Tissues • 293

Saroj K Parida
Nicole K MacLennan
Sherin U Devaskar
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 52
ASPHYXIA NEONATORUM: A MAJOR CAUSE OF MORTALITY AND MORBIDITY

John C Mulligan
Michael J Painter
Alexander C Allen
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 437
International Spinal Cord Injury Physical Therapy–Occupational Therapy Basic Data Set (Version 1.2)

Kim D. Anderson
Edelle C. Field-Fote
Mary Schmidt-Read
Research17 Aug 2020
Spinal Cord Series and Cases

Volume: 6, P: 1-8
Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: A worldwide collaborative project

David M S McHugh
Cynthia A Cameron
Wendy M Zakowicz
Research15 Feb 2011
Genetics in Medicine

Volume: 13, P: 230-254
Valedictory address

John Milne
Editorial10 May 2024
British Dental Journal

Volume: 236, P: 665-666
A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

Nicola S. Meagher
Linyuan Wang
Martin Köbel
Research25 Jun 2019
Modern Pathology

Volume: 32, P: 1834-1846
Gender Differences in Brain Metabolic and Plasma Catecholamine Responses to Alpha₂-Adrenoceptor Blockade

Mark E Schmidt
John A Matochik
William Z Potter
Research01 Apr 1997
Neuropsychopharmacology

Volume: 16, P: 298-310
Intracellular nitrate storage by diatoms can be an important nitrogen pool in freshwater and marine ecosystems

The accumulation and storage of nitrate by diatoms can contribute up to 1% of total pelagic nitrate and as much as 95% of total benthic nitrate, which indicates a potentially important contribution of diatoms to benthic nitrogen cycling, according to a global analysis

Peter Stief
Clemens Schauberger
Anja Kamp
ResearchOpen Access04 Jul 2022
Communications Earth & Environment

Volume: 3, P: 1-11
Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts

Erika Molteni
Christina M. Astley
Marc Modat
ResearchOpen Access25 Mar 2021
Scientific Reports

Volume: 11, P: 1-11
The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis

Alan Mark O’Doherty
Kevin Christophe Rue-Albrecht
David Evan MacHugh
ResearchOpen Access06 Feb 2019
Scientific Reports

Volume: 9, P: 1-15
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

Daniel R. Barnes
Matti A. Rookus
Antonis C. Antoniou
ResearchOpen Access15 Jul 2020
Genetics in Medicine

Volume: 22, P: 1653-1666
Single-cell analysis reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of ovarian cancer

An integrative single-cell transcriptomics study of ovarian cancer shows high and low stromal tumors have distinct classes in tumor-immune cell infiltration spectrum (hot vs cold). High stromal cell levels correlate with an immunosuppressive phenotype.

Linan Zhang
Sandra Cascio
Hatice Ulku Osmanbeyoglu
ResearchOpen Access05 Jan 2024
Communications Biology

Volume: 7, P: 1-14
The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

Inge M. M. Lakeman
Alexandra J. van den Broek
Marjanka K. Schmidt
ResearchOpen Access10 Jun 2021
Genetics in Medicine

Volume: 23, P: 1726-1737
How genetically heterogeneous is Kabuki syndrome?: MLL2 testing in 116 patients, review and analyses of mutation and phenotypic spectrum

Siddharth Banka
Ratna Veeramachaneni
Dian Donnai
Research30 Nov 2011
European Journal of Human Genetics

Volume: 20, P: 381-388
RNA sequencing provides exquisite insight into the manipulation of the alveolar macrophage by tubercle bacilli

Nicolas C. Nalpas
David A. Magee
David E. MacHugh
ResearchOpen Access08 Sept 2015
Scientific Reports

Volume: 5, P: 1-12
Evaluation of the economic impact of modified screening criteria for retinopathy of prematurity from the Postnatal Growth and ROP (G-ROP) study

John A. F. Zupancic
Gui-shuang Ying
Gui-shuang Ying
Research28 Feb 2020
Journal of Perinatology

Volume: 40, P: 1100-1108
Antigen receptor signaling: integration of protein tyrosine kinase functions

Idan Tamir
John C Cambier
Reviews22 Sept 1998
Oncogene

Volume: 17, P: 1353-1364
Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling

Clarissa S. Craft
Hero Robles
Erica L. Scheller
ResearchOpen Access22 Nov 2019
Scientific Reports

Volume: 9, P: 1-14
Loss of HOXC6 expression induces apoptosis in prostate cancer cells

Sumathi Ramachandran
Pengbo Liu
Carlos S Moreno
Research06 Jan 2005
Oncogene

Volume: 24, P: 188-198
Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2

Denise G. O’Mahony
Susan J. Ramus
Elizabeth Santana dos Santos
ResearchOpen Access19 Apr 2023
British Journal of Cancer

Volume: 128, P: 2283-2294
Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study

Ashley Weir
Eun-Young Kang
Susan J. Ramus
ResearchOpen Access02 Nov 2022
British Journal of Cancer

Volume: 128, P: 137-147
A hybrid computational approach for efficient Alzheimer’s disease classification based on heterogeneous data

Xuemei Ding
Magda Bucholc
KongFatt Wong-Lin
ResearchOpen Access27 Jun 2018
Scientific Reports

Volume: 8, P: 1-10
Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study

Suzanne C. Dixon-Suen
Christina M. Nagle
Penelope M. Webb
ResearchOpen Access20 Mar 2018
British Journal of Cancer

Volume: 118, P: 1123-1129
Expansion of phenotype and genotypic data in CRB2-related syndrome

Ryan E Lamont
Wen-Hann Tan
Anne M Slavotinek
Research23 Mar 2016
European Journal of Human Genetics

Volume: 24, P: 1436-1444
Determining breast cancer biomarker status and associated morphological features using deep learning

Gamble and Jaroensri et al. develop deep learning systems to predict breast cancer biomarker status using H&E images. Their models enable slide-level and patch-level predictions for ER, PR and HER2, with interpretability analyses highlighting specific histological features associated with these markers.

Paul Gamble
Ronnachai Jaroensri
Po-Hsuan Cameron Chen
ResearchOpen Access14 Jul 2021
Communications Medicine

Volume: 1, P: 1-12
Unraveling complexity and leveraging opportunities in uncommon breast cancer subtypes

Fresia Pareja
Rohit Bhargava
Steffi Oesterreich
ReviewsOpen Access24 Jan 2025
npj Breast Cancer

Volume: 11, P: 1-13
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk

Eileen O. Dareng
Jonathan P. Tyrer
Paul D. P. Pharoah
Amendments and CorrectionsOpen Access22 Mar 2022
European Journal of Human Genetics

Volume: 30, P: 630-631
Candidate gene linkage approach to identify DNA variants that predispose to preterm birth

Elise N.A. Bream
Cara R. Leppellere
Jeffrey C. Murray
Research20 Nov 2012
Pediatric Research

Volume: 73, P: 135-141
The storytelling arms race: origin of human intelligence and the scientific mind

Enrico Coen
Reviews12 Jun 2019
Heredity

Volume: 123, P: 67-78
Association between maternal stress and child sleep quality: a nationwide ECHO prospective cohort study

Sarah Dee Geiger
Aruna Chandran
H. Simhan
Research11 Oct 2024
Pediatric Research

Volume: 97, P: 980-988
Author Correction: Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts

Erika Molteni
Christina M. Astley
Marc Modat
Amendments and CorrectionsOpen Access12 Apr 2022
Scientific Reports

Volume: 12, P: 1-2

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