Nature Search

Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

Larry G. Johnson
John C. Olsen
Richard C. Boucher
Research01 Sept 1992
Nature Genetics

Volume: 2, P: 21-25
β-Adrenergic Sweat Responses in Cystic Fibrosis Heterozygotes with and without the ΔF508 Allele

John P Johnson
Elaine Louie
Jeffrey J Wine
Research01 Jun 1991
Pediatric Research

Volume: 29, P: 525-528
Herpesvirus vector gene transfer and expression of β–glucuronidase in the central nervous system of MRS VII mice

John H. Wolfe
Satish L. Deshmane
Nigel W. Fraser
Research01 Aug 1992
Nature Genetics

Volume: 1, P: 379-384
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

Devra P. Rich
Matthew P. Anderson
Michael J. Welsh
Research27 Sept 1990
Nature

Volume: 347, P: 358-363
Decreased lysosomal storage in the adult MPS VII mouse brain in the vicinity of grafts of retroviral vector-corrected fibroblasts secreting high levels of β-glucuronidase

Rosanne M Taylor
John H Wolfe
Research01 Jul 1997
Nature Medicine

Volume: 3, P: 771-774
Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland

Norbert Kartner
Olga Augustinas
John R. Riordan
Research01 Aug 1992
Nature Genetics

Volume: 1, P: 321-327
CFTR expression is regulated during both the cycle of the seminiferous epithelium and the oestrous cycle of rodents

Ann E.O. Trezise
Carol C. Linder
Manual Buchwald
Research01 Feb 1993
Nature Genetics

Volume: 3, P: 157-164
Origin of the herbicide binding site of acetolactate synthase

John V. Schloss
Lawrence M. Ciskanik
Drew E.Van Dyk
Research28 Jan 1988
Nature

Volume: 331, P: 360-362
Multiple targeted grassland restoration interventions enhance ecosystem service multifunctionality

Widespread grassland degradation poses major societal and environmental challenges. Here, the authors propose multiple targeted interventions as a crucial strategy for simultaneously enhancing grassland ecosystem services and improving their equitability.

Shangshi Liu
Susan E. Ward
Richard D. Bardgett
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-11
Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium

Ming Li
John D. McCann
Michael J. Welsh
Research28 Jan 1988
Nature

Volume: 331, P: 358-360
Cutting the carbon cost of academic travel

Travel is a key part of academic life, and the carbon emissions associated with it are high. Personal decisions to reduce flying can contribute to climate action, and need not compromise research.

John N. Quinton
Comments & Opinion13 Jan 2020
Nature Reviews Earth & Environment

Volume: 1, P: 13
Submucosal glands are the predominant site of CFTR expression in the human bronchus

John F. Engelhardt
James R. Yankaskas
James M. Wilson
Research01 Nov 1992
Nature Genetics

Volume: 2, P: 240-248
Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer

John H. Wolfe
Mark S. Sands
Edward H. Birkenmeier
Research31 Dec 1992
Nature

Volume: 360, P: 749-753
Alteration of Sulfation of Glycoconjugates, but Not Sulfate Transport and Intracellular Inorganic Sulfate Content in Cystic Fibrosis Airway Epithelial Cells

Nirupama K Mohapatra
Pi-Wan Cheng
Thomas F Boat
Research01 Jul 1995
Pediatric Research

Volume: 38, P: 42-48
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

Gerene M. Denning
Matthew P. Anderson
Michael J. Welsh
Research27 Aug 1992
Nature

Volume: 358, P: 761-764
Neural progenitor cell engraftment corrects lysosomal storage throughout the MRS VII mouse brain

Evan Y. Snyder
Rosanne M. Taylor
John H. Wolfe
Research23 Mar 1995
Nature

Volume: 374, P: 367-370
Cl^- Permeabilities in Red Blood Cells and Peripheral Blood Lymphocytes from Cystic Fibrosis and Control Subjects

Richard C Boucher
Dennis W Ross
John C Parker
Research01 Dec 1984
Pediatric Research

Volume: 18, P: 1336-1339
Developmental Differences of Cystic Fibrosis Transmembrane Conductance Regulator Functional Expression in Isolated Rat Fetal Distal Airway Epithelial Cells

R John Macleod
J R Hamilton
Neil B Sweezey
Research01 Jan 1994
Pediatric Research

Volume: 35, P: 45-49
Whole-genome sequencing of patients with rare diseases in a national health system

Whole-genome sequencing and phenotype data sharing are introduced in a national health system to streamline diagnosis and to discover coding and non-coding variants that cause rare diseases.

Ernest Turro
William J. Astle
Willem H. Ouwehand
Research24 Jun 2020
Nature

Volume: 583, P: 96-102
Decadal increases in carbon uptake offset by respiratory losses across northern permafrost ecosystems

The future of carbon dynamics in the northern high latitudes is uncertain yet represents an important potential feedback under climate change. This study uses a comprehensive observational dataset to show an increasing carbon sink in non-permafrost systems; in permafrost systems uptake was offset by loss.

Craig R. See
Anna-Maria Virkkala
Edward A. G. Schuur
ResearchOpen Access26 Jul 2024
Nature Climate Change

Volume: 14, P: 853-862
Antigen presentation by B cells enables epitope spreading across an MHC barrier

Increasing evidence suggests that antigen presentation by B cells is critical to the initiation of autoimmunity. Here, the authors demonstrate that tolerance breakdown is initiated outside of germinal centres and that B cells can directly instruct T cells to break tolerance and propagate autoimmune responses.

Cecilia Fahlquist-Hagert
Thomas R. Wittenborn
Søren E. Degn
ResearchOpen Access31 Oct 2023
Nature Communications

Volume: 14, P: 1-21
SMALL INTESTINAL MUCOSAL FATTY ACID UPTAKE AND ESTERIFICATION IN INFANTS AND CHILDREN

James E Heubi
John C Partin
Catherine A Mcgraw
Research01 Jun 1979
Pediatric Research

Volume: 13, P: 781-782
Reply to ‘Erosion and climate’

John N. Quinton
Gerard Govers
Richard D Bardgett
Correspondence29 Oct 2010
Nature Geoscience

Volume: 3, P: 738
The Relationship between Intracellular and Extracellular Potassium in Normal and Malnourished Subjects as Studied in Leukocytes

John Patrick
Research01 Jul 1978
Pediatric Research

Volume: 12, P: 767-770
Vegetation type is an important predictor of the arctic summer land surface energy budget

An international team of researchers finds high potential for improving climate projections by a more comprehensive treatment of largely ignored Arctic vegetation types, underscoring the importance of Arctic energy exchange measuring stations.

Jacqueline Oehri
Gabriela Schaepman-Strub
Scott D. Chambers
ResearchOpen Access31 Oct 2022
Nature Communications

Volume: 13, P: 1-12
Expression and characterization of the cystic fibrosis transmembrane conductance regulator

Richard J. Gregory
Seng H. Cheng
Alan E. Smith
Research27 Sept 1990
Nature

Volume: 347, P: 382-386
Chloride channels revisited

Chris Higgins
News & Views13 Aug 1992
Nature

Volume: 358, P: 536
Cellulose synthesis: Another brick in the wall

Keith Roberts
News & Views13 Sept 1984
Nature

Volume: 311, P: 105-106
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

The Hippo and mTORC1 pathways regulate growth control for proper organ development. Here, Gan et al. find that the Hippo pathway kinases LATS1 and LATS2 phosphorylate the mTORC1 component Raptor to attenuate mTORC1 activation.

Wenjian Gan
Xiaoming Dai
Wenyi Wei
Research03 Feb 2020
Nature Cell Biology

Volume: 22, P: 246-256
The impact of agricultural soil erosion on biogeochemical cycling

Soils are the main terrestrial reservoir of nutrients such as nitrogen and phosphorus, and of organic carbon. Data synthesis reveals that soil erosion can result in lateral fluxes of these nutrients at comparable magnitudes to those induced by fertilizer application and crop removal.

John N. Quinton
Gerard Govers
Richard D. Bardgett
Reviews18 Apr 2010
Nature Geoscience

Volume: 3, P: 311-314
Large loss of CO₂ in winter observed across the northern permafrost region

Winter warming in the Arctic will increase the CO₂ flux from soils. A pan-Arctic analysis shows a current loss of 1,662 TgC per year over the winter, exceeding estimated carbon uptake in the growing season; projections suggest a 17% increase under RCP 4.5 and a 41% increase under RCP 8.5 by 2100.

Susan M. Natali
Jennifer D. Watts
Donatella Zona
Research21 Oct 2019
Nature Climate Change

Volume: 9, P: 852-857
A second dose of a CFTR cDNA–liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea

CA Goddard
R Ratcliff
WH Colledge
Research01 Nov 1997
Gene Therapy

Volume: 4, P: 1231-1236
Tillage exacerbates the vulnerability of cereal crops to drought

Using soil redistribution and crop growth models, this study shows that as the duration and intensity of tillage increases, wheat and maize yields decrease. Under projected future climate conditions, the impact of crop yields from tillage erosion will be amplified due to reduced water availability.

John N. Quinton
Lena K. Öttl
Peter Fiener
Research23 Jun 2022
Nature Food

Volume: 3, P: 472-479
Agricultural land is the main source of stream sediments after conversion of an African montane forest

Jaqueline Stenfert Kroese
Pedro V. G. Batista
Mariana C. Rufino
ResearchOpen Access09 Sept 2020
Scientific Reports

Volume: 10, P: 1-15
Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma

Jonathan Wong
Emily Gruber
Jake Shortt
ResearchOpen Access22 Apr 2022
Leukemia

Volume: 36, P: 1654-1665
Evaluating CHARGE syndrome in congenital hypogonadotropic hypogonadism patients harboring CHD7 variants

Cheng Xu
Daniele Cassatella
Nelly Pitteloud
Research16 Nov 2017
Genetics in Medicine

Volume: 20, P: 872-881
The use of bio-monitoring to assess exposure in the electroplating industry

Helen Beattie
Chris Keen
Paul Smith
ResearchOpen Access02 Dec 2015
Journal of Exposure Science & Environmental Epidemiology

Volume: 27, P: 47-55

Search

Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

β-Adrenergic Sweat Responses in Cystic Fibrosis Heterozygotes with and without the ΔF508 Allele

Herpesvirus vector gene transfer and expression of β–glucuronidase in the central nervous system of MRS VII mice

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

Decreased lysosomal storage in the adult MPS VII mouse brain in the vicinity of grafts of retroviral vector-corrected fibroblasts secreting high levels of β-glucuronidase

Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland

CFTR expression is regulated during both the cycle of the seminiferous epithelium and the oestrous cycle of rodents

Origin of the herbicide binding site of acetolactate synthase

Multiple targeted grassland restoration interventions enhance ecosystem service multifunctionality

Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium

Cutting the carbon cost of academic travel

Submucosal glands are the predominant site of CFTR expression in the human bronchus

Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer

Alteration of Sulfation of Glycoconjugates, but Not Sulfate Transport and Intracellular Inorganic Sulfate Content in Cystic Fibrosis Airway Epithelial Cells

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

Neural progenitor cell engraftment corrects lysosomal storage throughout the MRS VII mouse brain

Cl^- Permeabilities in Red Blood Cells and Peripheral Blood Lymphocytes from Cystic Fibrosis and Control Subjects

Developmental Differences of Cystic Fibrosis Transmembrane Conductance Regulator Functional Expression in Isolated Rat Fetal Distal Airway Epithelial Cells

Whole-genome sequencing of patients with rare diseases in a national health system

Decadal increases in carbon uptake offset by respiratory losses across northern permafrost ecosystems

Antigen presentation by B cells enables epitope spreading across an MHC barrier

SMALL INTESTINAL MUCOSAL FATTY ACID UPTAKE AND ESTERIFICATION IN INFANTS AND CHILDREN

Reply to ‘Erosion and climate’

The Relationship between Intracellular and Extracellular Potassium in Normal and Malnourished Subjects as Studied in Leukocytes

Vegetation type is an important predictor of the arctic summer land surface energy budget

Expression and characterization of the cystic fibrosis transmembrane conductance regulator

Chloride channels revisited

Cellulose synthesis: Another brick in the wall

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

The impact of agricultural soil erosion on biogeochemical cycling

Large loss of CO₂ in winter observed across the northern permafrost region

A second dose of a CFTR cDNA–liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea

Tillage exacerbates the vulnerability of cereal crops to drought

Agricultural land is the main source of stream sediments after conversion of an African montane forest

Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma

Evaluating CHARGE syndrome in congenital hypogonadotropic hypogonadism patients harboring CHD7 variants

The use of bio-monitoring to assess exposure in the electroplating industry

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