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Showing 1–2 of 2 results
Advanced filters: Author: Jon D Piganelli Clear advanced filters
  • A cure for diabetes could entail an effective cell replacement therapy through generation of new insulinproducing cells. In this study, we show that inhibition of focal adhesion kinase activity results in transdifferentiation of a subset of peri-islet acinar cells into functional insulin producing β-like cells.

    • Shakti Dahiya
    • Mohamed Saleh
    • Farzad Esni
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16
  • The identity of self antigens targeted in various autoimmune diseases is often unknown. Haskins and colleagues identify a chromagranin A epitope whose presentation by I-Ag7 involves an unusual peptide-binding mode.

    • Brian D Stadinski
    • Thomas Delong
    • Kathryn Haskins
    Research
    Nature Immunology
    Volume: 11, P: 225-231