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Showing 1–3 of 3 results
Advanced filters: Author: Jon D. Laman Clear advanced filters

  • The gut microbiota controls immunity and brain function, but its role in cognitive aging is unclear. Boehme et al. found that fecal microbiota transplantation from young into aged mice attenuated cognitive impairments and reversed differences in hippocampal metabolites, and some aspects of peripheral and brain immunity.

    • Rochellys Diaz Heijtz
    • Ayoze Gonzalez-Santana
    • Jon D. Laman
    News & Views
    Nature Aging
    Volume: 1, P: 625-627

  • Microglia are the macrophages of the CNS, with innate neuroimmune function, and play important roles in tissue homeostasis, CNS development and neurodegeneration. Here human microglial gene expression profiles were generated. Human and mouse microglia were highly similar, except for aging-regulated genes, indicating that microglial aging differs between humans and mice.

    • Thais F Galatro
    • Inge R Holtman
    • Bart J L Eggen
    Research
    Nature Neuroscience
    Volume: 20, P: 1162-1171