Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–11 of 11 results
Advanced filters: Author: Jon Slate Clear advanced filters

  • Phytochrome photoreceptors are master regulators of plant development. This paper describes 3D structures of soybean phytochrome A in both Pr (inactive) and Pfr (signalling) states, revealing changes that might transmit the light signal to the cell.

    • Soshichiro Nagano
    • David von Stetten
    • Jon Hughes
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • The structures of four plant phytochrome sensory modules, including an A-type phytochrome, illuminate the function of these red/far-red photoreceptors and suggest the existence of a nuclear localization signal specific to the phytochrome A lineage.

    • Soshichiro Nagano
    • Kaoling Guan
    • Jon Hughes
    Research
    Nature Plants
    Volume: 6, P: 581-588

  • Eliciting broadly neutralizing antibodies (bnAbs) is a primary HIV vaccine goal, but available immunogens expose epitopes for development of non-nAbs. Here, the authors use computational and structure-guided design to develop improved native-like envelope trimers and analyze Ab response in animal models.

    • Daniel W. Kulp
    • Jon M. Steichen
    • William R. Schief
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14

  • FadR is a regulator of fatty acid metabolism in bacteria, and contains a binding site for acyl-CoA. Here, Shi et al. present a structure of V. cholerae FadR and show that a unique C-terminal extension comprises a second acyl-CoA binding site, perhaps rendering V. choleraeFadR a more efficient regulator.

    • Wei Shi
    • Gabriela Kovacikova
    • F. Jon Kull
    Research
    Nature Communications
    Volume: 6, P: 1-10

  • A survey of protein structures identifies widespread lysine–cysteine cross-links in functionally diverse proteins across all domains of life and in various structural motifs, where these redox switches control enzyme catalysis and/or ligand binding.

    • Fabian Rabe von Pappenheim
    • Marie Wensien
    • Kai Tittmann
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 18, P: 368-375

  • Wild Soay sheep rams with large horns have more offspring, yet there is considerable genetic variation at RXFP2, a locus strongly implicated in horn size (with different alleles conferring either large or small horns); this study finds that although the larger horn allele leads to more offspring, the smaller horn allele leads to increased survival, meaning heterozygous rams (which develop medium-sized horns) have high reproductive success and survival, providing a rare example of heterozygote advantage.

    • Susan E. Johnston
    • Jacob Gratten
    • Jon Slate
    Research
    Nature
    Volume: 502, P: 93-95

  • The great tit (Parus major) is known for its complex social-cognitive behaviour. Here, the authors sequence genomes of the great tit and show genes related to learning and cognition in regions under positive selection, as well as neuronal non-CpG methylation patterns similar to those observed in mammals.

    • Veronika N. Laine
    • Toni I. Gossmann
    • Martien A. M. Groenen
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-9

  • Sperm morphology is remarkably variable yet its genetic architecture is poorly known. Now, sperm morphology variation in zebra finches is shown to be largely explained by an inversion polymorphism on the Z chromosome acting as a supergene.

    • Kang-Wook Kim
    • Clair Bennison
    • Jon Slate
    Research
    Nature Ecology & Evolution
    Volume: 1, P: 1168-1176

  • Terry Burke, Mark Blaxter, David Lank and colleagues report a reference genome sequence of the ruff and analysis of the three distinct male morphs of this bird species. They identify a ‘supergene’ consisting of a fixed inversion in two of the morphs and identify candidate reproductive trait genes in this region.

    • Clemens Küpper
    • Michael Stocks
    • Terry Burke
    ResearchOpen Access
    Nature Genetics
    Volume: 48, P: 79-83

  • The genome of the zebra finch — a songbird and a model for studying the vertebrate brain, behaviour and evolution — has been sequenced. Comparison with the chicken genome, the only other bird genome available, shows that genes that have neural function and are implicated in the cognitive processing of song have been evolving rapidly in the finch lineage. Moreover, vocal communication engages much of the transcriptome of the zebra finch brain.

    • Wesley C. Warren
    • David F. Clayton
    • Richard K. Wilson
    ResearchOpen Access
    Nature
    Volume: 464, P: 757-762