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Showing 1–4 of 4 results

Advanced filters: Author: Jonas F. Dorn Clear advanced filters

Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease

Diagnostic blood-based biomarkers of pediatric IBD are limited. Here, the authors demonstrate a diagnostic lipidomic signature, comprising only of two molecular lipids. Translation of this signature into a scalable test has the potential to support clinical decision making.

Samira Salihovic
Niklas Nyström
Jonas Halfvarson
ResearchOpen Access03 Jun 2024
Nature Communications

Volume: 15, P: 1-15
A small GTPase molecular switch regulates epigenetic centromere maintenance by stabilizing newly incorporated CENP-A

The histone H3 variant CENP-A defines centromeric chromatin, but it is not known how it is maintained at these loci. The CENP-A licensing factor HsKNL2, the small GTPases Cdc42 and Rac, and their regulators Ect2 and MgcRacGAP, coordinately promote the stability of newly loaded CENP-A at centromeres.

Anaïck Lagana
Jonas F. Dorn
Paul S. Maddox
Research21 Nov 2010
Nature Cell Biology

Volume: 12, P: 1186-1193
Positional stability of single double-strand breaks in mammalian cells

Evi Soutoglou
Jonas F. Dorn
Tom Misteli
Research07 May 2007
Nature Cell Biology

Volume: 9, P: 675-682
X-ray based virtual histology allows guided sectioning of heavy ion stained murine lungs for histological analysis

Jonas Albers
M. Andrea Markus
Christian Dullin
ResearchOpen Access16 May 2018
Scientific Reports

Volume: 8, P: 1-10

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