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Showing 1–4 of 4 results

Advanced filters: Author: Jonas Renz Clear advanced filters

In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution

A CRISPR-based strategy for screening genes that affect clonal expansion finds that genes that are frequently mutated in squamous cell carcinoma converge on a TNF signalling module involving macrophages.

Peter F. Renz
Umesh Ghoshdastider
Ataman Sendoel
ResearchOpen Access17 Jul 2024
Nature

Volume: 632, P: 419-428
Nuclear myosin VI maintains replication fork stability

Whether actin and associated molecules have roles in the nucleus is an active area of study. Here Shi et al. report a nuclear function of the actin-based motor myosin VI in protecting stalled replication forks from nuclease-mediated degradation.

Jie Shi
Kristine Hauschulte
Hans-Peter Wollscheid
ResearchOpen Access24 Jun 2023
Nature Communications

Volume: 14, P: 1-13
Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona

Antibody pre-adsorption on the nanocarrier surface is a mild modification strategy that preserves antibody functionality and targeting ability.

Manuel Tonigold
Johanna Simon
Volker Mailänder
Research18 Jun 2018
Nature Nanotechnology

Volume: 13, P: 862-869
Leveraging electronic medical records to evaluate a computerized decision support system for staphylococcus bacteremia

Julia Palm
Ssuhir Alaid
André Scherag
ResearchOpen Access28 Mar 2025
npj Digital Medicine

Volume: 8, P: 1-9